Bioactive materials of natural origin have great demand in industry and medicine due to their versatility useful properties. The main purpose this work is prepare biocomposites for the dual modified silk fibroin (Bombyx mori L.), which protects against destructive effects bioactive, antioxidant ultraviolet rays. For purpose, an aqueous extract autumn leaves anthocyanin-rich smoke tree plant (Co...

Silk scaffolds having biomimetic hierarchical porous structures were achieved by carefully tuning liquid-liquid separation in regenerated silk fibroin solutions. Such scaffolds show greatly enhanced cellular responses.

Low energy plasma has been introduced to treat the surface of Thai silk fibroin which should be enhanced for cell adhesion due to its native hydrophobic surface. Plasma surface treatment could introduce desirable hydrophilic functionalities on the surface without using any chemicals. In this work, nitrogen glow discharge plasma was generated by a low energy AC50Hz power supply system. The plasm...

This perspective provides an overview of the micro-/nanofabrication methods developed for structural biopolymers, highlighting recent advances in rapid and ease construction complex multifunctional silk fibroin-based devices by integrating top-down manufacturing with bottom-up molecular self-assembly. Of particular interest is development a new nanofabrication strategy that employs templated cr...

Miscibility is an important issue in biopolymer blends for analysis of the behavior of polymer pairs through the detection of phase separation and improvement of the mechanical and physical properties of the blend. This study presents the formulation of a stable and one-phase mixture of collagen and regenerated silk fibroin (RSF), with the highest miscibility ratio between these two macromolecu...

A locus responsible for the Nd-s mutation of the silkworm, Bombyx mori, has been mapped very close to or within the fibroin light (L) chain gene on the 14th chromosome (Takei, F., K. Kimura, S. Mizuno, T. Yamamoto, and K. Shimura, 1984, Jpn. J. Genet., 59:307-313). A strain of B. mori carrying the homozygous Nd-sD mutation (Nd-sD/Nd-sD; Nd-sD is allelic to Nd-s) secretes less than 0.3% of fibro...

Many studies have demonstrated that in vitro shear stress conditioning of endothelial cell-seeded small-diameter vascular grafts can improve cell retention and function. However, the laminar flow and pulsatile flow conditions which are commonly used in vascular tissue engineering and hemodynamic studies are quite different from the actual physiological pulsatile flow which is pulsatile in natur...

Silk is a functional protein biomaterial produced by variety of insects like flies, silkworms, scorpions, spiders, and mites. synthesized silkworms extensively studied for its applications in tissue engineering wound healing. undoubtedly natural biocompatible material with humans has role medical treatments from ancient times. The silk worm comprises two types proteins namely fibroin sericin. m...

The distal upstream region of the fibroin gene, -238 to -73, is known to contain the cis-acting element(s) responsible for tissue-specific transcription enhancement in vitro. To identify factor(s) trans-acting on this region, we have developed a modified nitrocellulose blot protein-DNA binding procedure that detects DNA-protein complexes via protein-protein interaction. A protein that does not ...