Nucleocytoplasmic transport is mediated by the interaction of transport factors (TFs) with disordered phenylalanine-glycine (FG) repeats that fill the central channel of the nuclear pore complex (NPC). However, the mechanism by which TFs rapidly diffuse through multiple FG repeats without compromising NPC selectivity is not yet fully understood. In this study, we build on our recent NMR investi...

The present study was designed to determine the effect of fenugreek seed extract (FG) on endurance capacity in male mice aged 4 wk. Mice were given orally either vehicle or FG (150, 300 mg/kg body weight) by stomach intubation for 4 wk. The 300 mg/ kg FG group showed a significant increase in swimming time to exhaustion as compared to the control group. In the FG groups, blood lactate concentra...

The copper(1) complex [(TMPA)Cu(RCN)]+ (1) binds 0 2 forming [{ (TMPA)Cu}2(02)]2+ (2), with trans-y-1, 2 peroxo-coordination. Ligands with quinolyl groups substituting for the pyridyl donors in TMPA cause dramatic changes in the course of reaction, in one case stabilizing a CdO2 1:l adduct [(BQPA)Cu(02)]+ (6 ) . The kinetics/thermodynamics are compared. Reaction of 1 with (F 8-TPP)Fe(II)pip2 (8...

UNLABELLED Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a shield to protect the bacteria from phagocytic clearance. This communication describes ...

Nuclear pore complexes (NPCs) form aqueous conduits in the nuclear envelope and gate the diffusion of large proteins between the cytoplasm and nucleoplasm. NPC proteins (nucleoporins) that contain phenylalanine-glycine motifs in filamentous, natively unfolded domains (FG domains) line the diffusion conduit of the NPC, but their role in the size-selective barrier is unclear. We show that deletio...

PURPOSE To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses. METHODS One hundred twenty-eight male and female New Zealand white rabbits underwent intraperitoneal infection subsequent ileal anastomosis surgery were divided randomly into 4 groups, includ...

Similar to the very vast prior literature on analyzing laminated composite structures, “higher-order” and “layer-wise higher-order” plate and shell theories for functionally-graded (FG) materials and structures are also widely popularized in the literature of the past two decades. However, such higher-order theories involve (1) postulating very complex assumptions for plate/shell kinematics in ...

Porous conduits provide a protected pathway for nerve regeneration, while still allowing exchange of nutrients and wastes. However, pore sizes >30 µm may permit fibrous tissue infiltration into the conduit, which may impede axonal regeneration. Coating the conduit with Fibrin Glue (FG) is one option for controlling the conduit's porosity. FG is extensively used in clinical peripheral nerve repa...

The concentrations of metabolites in human plasma after ingestion of flavanone glycosides (FG) and their aglycones (FA) in lemon were examined. FG consisting abundantly of eriocitrin were prepared from lemon peel and FA consisting abundantly of eriodictyol were prepared from FG by treatment with beta-glucosidase. Eriodictyol, homoeriodictyol, and hesperetin in plasma up to 4 h after ingestion o...

Let $FG$ be the group algebra of a finite $p$-group $G$ over a
 field $F$ characteristic $p$ and let $*$ the
 classical involution $FG$. The $*$-unitary subgroup $FG$,
 denoted by $V_*(FG)$, is defined to set all normalized
 units $u$ satisfying property $u^*=u^{-1}$. In this paper we
 give recursive method how compute order for certain non-commutative algebras.
 A...