Myocardial substrate metabolism was studied in 13 subjects at the time of diagnostic cardiac catheterization by means of palmitic acid-(14)C infusion with arterial and coronary sinus sampling. Two subjects were considered free of cardiac pathology and all, with one exception, demonstrated lactate extraction across the portion of heart under study. Data for this single lactate-producing subject ...

Approximently 10,000 years ago, civilization began in the Fertile Crescent of Mesopotamia around the river valleys of the Euphrates and the Tiger rivers. It was agriculture that allowed these civilizations to prosper and the river water that allowed agriculture. The number of people in the world has grown signi cantly since then increasing the demand for food production. Agriculture has been fo...

Blue-veined cheeses in general undergo a pronounced lipolysis. The aim of this work was to determine the evolution free fatty acids (FFA) Valdeón cheese during ripening, comparing made from raw and pasteurized milk. effect season on FFA milk also studied. Cheeses with showed highest concentrations FFA, reaching values 23,081.9 mg 100 g?1 dry matter at end compared (7327.1 matter), both cases pr...

Elevated free fatty acids (FFA) are implicated with insulin resistance at the cellular level. However, the contribution of whole body lipid kinetics to FFA-induced insulin resistance is not well understood, and the effect of exercise and diet on this metabolic defect is not known. We investigated the effect of 12 wk of exercise training with and without caloric restriction on FFA turnover and o...

To determine the effects of an increase in lipolysis on the glycogenolytic effect of epinephrine (EPI), the catecholamine was infused portally into 18-h-fasted conscious dogs maintained on a pancreatic clamp in the presence [portal (Po)-EPI+FFA, n = 6] and absence (Po-EPI+SAL, n = 6) of peripheral Intralipid infusion. Control groups with high glucose (70% increase) and free fatty acid (FFA; 200...

In this study, polyphenylsulfone (PPSU) hollow fiber membrane was fabricated via a wet spinning method with the addition of ethylene glycol (EG) in the range of 0-10 wt% as the additive. The EG was added to improve the membrane pore formation and interconnectivity for better membrane contactor performance in extracting and removing the free fatty acid (FFA) from crude palm oil (CPO). Four diffe...

OBJECTIVE To test the hypothesis that free fatty acid (FFA) and muscle glycogen modify exercise-induced regulation of PDH (pyruvate dehydrogenase) in human skeletal muscle through regulation of PDK4 expression. RESEARCH DESIGN AND METHODS On two occasions, healthy male subjects lowered (by exercise) muscle glycogen in one leg (LOW) relative to the contra-lateral leg (CON) the day before the e...

1548-9213/04 5.00 ©2006 Int. Union Physiol. Sci./Am. Physiol. Soc. tions; they provide a major portion of physiological energy needs (42), are important constituents in the synthesis of complex lipids, and play critical roles in cell signaling (18). Most FFA are obtained from circulating plasma FFA, the levels of which are regulated by the rate at which FFA are generated, predominantly by adipo...