Breast cancer is the most common malignancy diagnosed in women in the United States. Many breast cancer survivors are concerned that cancer treatment will compromise their reproductive potential. Despite this concern, most women receive limited information addressing preservation of fertility before initiating adjuvant chemotherapy. Historically, the supraphysiologic levels of estrogens associa...

The demographic transition --the move from a high fertility/high mortality regime into low fertility/low regime-- is one of the most fundamental transformations that countries undertake. To study transitions across time and space, we compile data set birth death rates for 186 spanning more than 250 years. We document (i) has been completed or ongoing in nearly every country; (ii) speed increase...

The goals and rhetoric of The Oncofertility Consortium [1] are aimed toward preserving cancer patients’ reproductive choices and facilitating their reproductive autonomy after cancer. While the end goals of oncofertility research are oriented toward safeguarding the possibility of biological reproduction for women and girls facing cancer treatments that may affect their reproductive capacity, c...

This paper reviews progress that has been made over the last 50 years and discusses how the development and application of new technologies have been utilized to increase our understanding of the development and selection of the dominant follicle. Our increased knowledge from research carried out worldwide, has demonstrated that the development of the dominant follicle, and importantly the prod...

Purpose To assess the efficacy of fertility preservation (FP) and the impact of chemotherapy on the reproductive potential of Japanese patients with breast cancer. Methods Sixty-two patients with breast cancer visited the authors' centers from October, 2003 to June, 2015. They were divided into two groups according to the treatment: oocyte or embryo vitrification for FP before cancer treatmen...

Cancer may be detected at any age and could affect children, and reproductive age women as well. In recent years, cancer treatment has become less destructive and more specific. As a result, survival rates and quality of life following successful treatment have continuously improved. Cancer treatment typically involves surgery, chemo- or radiation therapy, or the combinations of these. These in...

Cryopreservation of human spermatozoa-introduced in the 1960's-has been recognized as an efficient procedure for management of male fertility before therapy for malignant diseases, vasectomy or surgical infertility treatments, to store donor and partner spermatozoa before assisted reproduction treatments and to ensure the recovery of a small number of spermatozoa in severe male factor infertili...