There are numerous studies presenting the beneficial effect of bisphosphonates (BPs) on bone disease of patients suffering from beta-thalassemia major (TM). Although BPs have been widely used, adverse events have been described including atypical femoral fractures (AFF). In the present case, a male adult patient suffering from TM sustained an AFF fulfilling all major and two minor criteria. Bef...

Atypical femoral fractures are uncommon fractures that are often associated with extended bisphosphonate use. They occur in the proximal or middle diaphyseal portion of the femur with a short oblique pattern and have relatively thickened cortices. Prodromal pain symptoms vary and bilateral involvement is common. Because delayed or complicated healing adversely affects treatment, fixation with a...

The authors describe a novel technique of anterograde femoral intramedullary nail fixation for hip fracture using the starting guide pin as a blocking screw. This cost-effective technique uses fluoroscopic radiography to ensure the guidewire is within the posterior aspect of the femur on a lateral view, thereby minimizing the risk of anterior cortical femoral fractures.

At the Trauma Unit of Pisa we performed an observational study reviewing nineties that about 200 patients were treated and underwent surgery for femoral neck fracture from 1998 to 2005. The clinical and radiographic results obtained were discrete, with a mortality of 42.5%, the survivors are still having a good quality of life.

In this paper we compare the prevalence of osteoarthritis (OA) of hip and knee joints on skeletons series and relations between them. OA was registered from 166 individuals of Neolithic and protohistorical periods. Between Neolithic and Iron Age periods the ratio [hip OA/ knee OA] increases with diminution of knee OA prevalence; the ratio [patello-femoral OA / tibio-femoral OA] rather tends to ...

Fractures of the proximal femur are one of the greatest challenges facing the medical community, constituting a heavy socioeconomic burden worldwide. Controversy exists regarding the optimal treatment for patients with unstable trochanteric proximal femoral fractures. The recognised treatment alternatives are extramedullary fixation usually with a sliding hip screw and intramedullary fixation w...

Roughly half of the femoral fracture patients diagnosed with AFF according to the criteria suggested by a task force of the American Society for Bone and Mineral Research (ASBMR) have not undergone bisphosphonate (BP) therapy. One suspected cause of such fractures is severe bone loss due to osteomalacia, but the pathogenesis remains unknown. We report a case of an 84-year-old woman with AFF not...

OBJECTIVES To establish the primary determinants of operative radiation use during fixation of proximal femur fractures. DESIGN Retrospective cohort study. SETTING Level I trauma centre. COHORT 205 patients treated surgically for subtrochanteric and intertrochanteric femoral fractures. MAIN OUTCOME MEASURES Fluoroscopy time, dose-area-product (DAP). RESULTS Longer fluoroscopy time was...

UNLABELLED We present a 77-year-old woman with no histor of trauma, or associated with low-energy trauma, admitted to our clinic after three weeks of a left femoral fracture threated in Orthopedic Clinic. The patient was in treatment with bisphosphonates over 10 years for osteoporosis. DISCUSSION AND CONCLUSIONS The causal re lationship between prolonged bisphosphonate use and the occurrence ...

Objective : The aim of this study is to evaluate both the anatomical and functional consequences of our treatment protocol of diaphyseal femoral fractures in children under 6 years old Methods : We conducted a retrospective analysis of a series containing 50 children in Strasbourg University Hospital whom had traumatic diaphyseal femoral fractures and underwent conservative treatment by tractio...