BACKGROUND Kawasaki disease (KD) is a febrile childhood vasculitis of unknown etiology. The diagnosis is highly concerning as over a quarter of children who fail to receive timely treatment with intravenous immunoglobulin (IVIG) will develop coronary aneurysms. Diagnosis relies on proper symptomatology and is supported by non-specific markers of inflammation. Previous studies have identified el...

Febrile seizures are the commonest acute neurological disorder of early childhood. Studies suggested that febrile seizures are previous acute events from a more serious neurological problem. Due to neuron-specific enolase is generally accepted as a marker for neuropathological processes in the brain, 16 pediatric patients were studied during their first seizures and a year after it. Neuron-spec...

BACKGROUND Dengue virus (DENV) infection is prevalent across tropical regions and may cause severe disease. Early diagnosis may improve supportive care. We prospectively assessed the Standard Diagnostics (Korea) BIOLINE Dengue Duo DENV rapid diagnostic test (RDT) to NS1 antigen and anti-DENV IgM (NS1 and IgM) in children in Cambodia, with the aim of improving the diagnosis of DENV infection. ...

© 2018 Elsevier Masson rrent limb and facial ema with R92Q mutation: n-febrile late-onset tumour osis factor receptorheterozygous mutation, disclosing probable non-febrile lateonset TRAPS. TRAPS usually begins during the first two decades [1]. Some cases of late-onset TRAPS have been described, with a median age of 32 years [2]. However, only few patients with an onset after 45 years have been ...

BACKGROUND Febrile seizures are the most common seizures in children, but their pathogenesis remains unknown. Some studies have suggested an association between the light-dependent secretion of melatonin and the occurrence of febrile seizures. The diurnal and seasonal occurrence of febrile seizures could clarify the role daylight plays in febrile seizures. METHODS In Finland, summer days are ...

BACKGROUND Blood transfusion is imperative when treating certain patients; however, it is not risk free. In addition to the possible transmission of contagious infectious diseases, incidents can occur immediately after transfusion and at a later time. AIMS This study aimed to examine the immediate transfusion incidents reported in a regional blood bank in the state of Minas Gerais between Dec...

Correspondence to: Dr I K Maconochie, Department of Paediatric Accident and Emergency, St Mary’s Hospital, London W2 1NY, UK; i.maconochie@ imperial.ac.uk _________________________ D r Tomisaku Kawasaki published a case series of 50 children in 1967 who were febrile and all had a rash, non-exudative conjunctivitis, erythema of the palms and soles of the feet, and cervical lymphadenopathy. This ...

Background: Febrile seizures are the most common convulsive disorder in children. There is growing evidence that vitamin D can affect gene expression and modulate various cell metabolisms. Also vitamin D may have a role in the etiology of febrile seizures. We aimed to explore vitamin D status in children with febrile seizure. Materials and Methods: This cross-sectional study was conducted on 40...