An asymmetrical FIA merging-zones manifold based on the dual injection of two sample microvolumes was developed for the simultaneous determination of salicylic acid and acetylsalicylic acid in pharmaceutical preparations at a sampling frequency of 30/h. The complex formed between the Fe(III) reagent continuously introduced in the system and salicylic acid was monitored photometrically at 520 nm...

words count: 242 ABSTRACT Manganese enhanced MRI (MEMRI) offers many possibilities such as tract tracing and functional imaging in vivo. Mn is however neurotoxic and may induce symptoms s of Mn-induced neurotoxicity are not clear. In this study, we combine synchrotron X-ray fluorescence microprobe (SR-XRF) and MEMRI techniques to investigate spatial distribution of Mn within the rat hippocampus...

This experiment was conducted to investigate the effects of iron from an amino acid complex (Availa-Fe) on the iron status of neonatal and suckling piglets. A total of 24 gestating sows (Landrace×Large White) were randomly allocated to three dietary treatments. The control diet contained 80 mg kg Fe from ferrous sulfate heptahydrate (FeSO4⋅7H2O), while the two experimental diets were supplement...

A granuloma pouch was formed on the back of rats by the original method of SELYE. Seven days when granuloma tissue reached its maximum, 35S labeled ChS, 59Fe labeled ChS-Fe, labeled ferric ammoninum citrate and colloidal 198Au were injected into the pouch and their absorption and organ distribution examined and compared with the results in the case where 59Fe labeled ferric ammoninum citrate an...

The age and origin of the quartz-amphibole-pyroxene (qap) gneiss from the island of Akilia, southern West Greenland, have been the subject of intense debate since the light C-isotope composition of graphite inclusions in apatite was interpreted to indicate the presence of Earth's earliest biological activity. Although this claim for biogenic relicts has been vigorously challenged, the possibili...

Dissolved Fe(II) in seawater is deemed an important micronutrient for microbial organisms, but its analysis is challenging due to its transient nature. We conducted a series of Fe(II) method comparison experiments, where spikes of 5 to 31 nM Fe(II) were added to manipulated seawaters with varying dissolved oxygen (37 to 156μM) concentrations. The observed Fe(II) concentrations from four analyti...

Introduction: Fe (T1/2= 1.49 My) is a key a short-lived radioactive nuclide because it is the only one for which an origin from irradiation by cosmic rays is impossible. Fe is a neutron-rich nuclei and its production rate during irradiation processes around the early Sun (because of the low cross sections of appropriate reactions and of the low abundance of targets) is at least two orders of ma...

We present a systematic analysis of XMM-Newton observations of 8 cool-core clusters of galaxies and determine the Fe distribution in the intracluster medium relative to the stellar distribution in the central dominant galaxy (CDG). Our analysis shows that the Fe is significantly more extended than the stellar mass in the CDG in all of the clusters in our sample, with a slight trend of increasin...

Pyruvate formate-lyase activating enzyme (PFL-AE) generates the catalytically essential glycyl radical of PFL. It is a member of the so-called "radical-SAM superfamily" of enzymes that use a [4Fe-4S] cluster and S-adenosylmethionine (AdoMet or SAM) to catalyze diverse radical-mediated reactions. Evidence suggests that this class of enzymes operate by common initial steps involving the generatio...

Mannitol (M) and deferoxamine (DFO) can each protect against myohemoglobinuric acute renal failure (MH-ARF). This study assessed M-DFO interactions during MH-ARF to help discern mechanisms of renal injury, and to define whether M + DFO exerts additive or synergistic antioxidant/cytoprotective effects. Rats subjected to the glycerol model of MH-ARF were treated with (a) M; (b) DFO; (c) M + DFO; ...