Continuous fluorescence microphotolysis (CFM) and fluorescence correlation spectroscopy (FCS) permit measurement of molecular mobility and association reactions in single living cells. CFM and FCS complement each other ideally and can be realized using identical equipment. So far, the spatial resolution of CFM and FCS was restricted by the resolution of the light microscope to the micrometer sc...

The paper is devoted to the analysis of problems appearing in optimisation and improvement of the powerbandwidth efficiency of digital communication feedback systems (FCS). There is shown that unlike digital systems, adaptive FCS with the analogue forward transmission allow full optimisation and derivation of optimal transmission-reception algorithm approaching their efficiency to the Shannon b...

Fluorescence correlation spectroscopy (FCS) is a powerful technique to investigate molecular dynamics with single molecule sensitivity. In particular, in the life sciences it has found widespread application using fluorescent proteins as molecularly specific labels. However, FCS data analysis and interpretation using fluorescent proteins remains challenging due to typically low signal-to-noise ...

Background Based on successive Health Interview Surveys (HIS), it has been demonstrated that also in Belgium obesity, measured by means of a self-reported body mass index (BMI in kg/m2), is a growing public health problem that needs to be monitored as accurately as possible. Studies have shown that a self-reported BMI can be biased. Consequently, if the aim is to rely on a self-reported BMI, ad...

Feed-forward inhibition (FFI) represents a powerful mechanism by which control of the timing and fidelity of action potentials in local synaptic circuits of various brain regions is achieved. In the cochlear nucleus, the auditory nerve provides excitation to both principal neurons and inhibitory interneurons. Here, we investigated the synaptic circuit associated with fusiform cells (FCs), princ...

O objetivo deste estudo foi identificar os Fatores Críticos de Sucesso (FCS) em projetos da Indústria 4.0, para apoiar a área gestão no mapeamento e desenvolvimento atividades durante as fases iniciação, planejamento, execução encerramento voltados 4.0. adotou como estratégia pesquisa uma Revisão Sistemática Literatura (RSL) cuja análise constituída por 56 artigos, devidamente categorizados, o ...

1. Introduction Our understanding of polymer dynamics has greatly improved due to the reptation model and the scaling ideas. [1] According to scaling and reptation theory, the diffusion coefficient in semidilute or concentrated regimes is related to the molar mass and polymer concentration by D ~ M-2 c-1.75 and D ~ M-2 c-3 for good-solvent and θ-solvent conditions, respectively. In a limited ra...

The peptidyl transferase center of the domain V of large ribosomal RNA in the prokaryotic and eukaryotic cytosolic ribosomes acts as general protein folding modulator. We showed earlier that one part of the domain V (RNA1 containing the peptidyl transferase loop) binds unfolded protein and directs it to a folding competent state (FCS) that is released by the other part (RNA2) to attain the fold...

We analyze in detail the interaction correction to full counting statistics FCS of electron transfer in a quantum contact originating from the electromagnetic environment surrounding the contact. The correction can be presented as a sum of two terms, corresponding to elastic-inelastic electron transfer. Here we primarily focus on the inelastic correction. For our analysis, it is important to un...

1. The neural activity of the nerve cord of Hirudo medicinalis has been recorded in unrestrained animals by means of chronically implanted electrodes. 2. The Fast Conducting System (FCS) is inactive both in motionless animals and during various kinds of active behaviour (creeping, swimming, ventilation). 3. Photic and tactile stimuli applied to a motionless animal elicit a FCS discharge, which ...