The central goal of this project is a deeper understanding of the dynamic adjustment of mobile sandy sediments to fluid forcing in and near the surf zone at small (1cm to 10m) and intermediate (10m to 100m) horizontal scales. The effort is motivated by the dual need to develop more realistic models of fluid-sediment interactions in the nearshore zone, and for suitable in situ measurement techni...

We explicitly consider entire families of software requirements; this enables us to configure family members using features. Our goal is to avoid feature interaction problems by a software engineering approach. Naive feature orientation does not scale due to complexity problems. But we can structure a family of requirements into requirements modules to make it easier to maintain. We then can co...

waves, a systolic ejection murmur, and wide splitting of the second heart sound. The electrocardiogram was characterized by a short PR interval, increasedQRS amplitude, and persistent ST depression. There was little or no cardiomegaly but some pulmonary artery prominence. There was no evidence of subaortic stenosis or coronary artery disease in three members who were catheterized, but mild infu...

Bardet-Biedl syndrome (BBS) is one of the rare autosomal recessive disorders that affect multiple organs of the body. The signs and symptoms of this condition vary among affected individuals, even among members of the same family. We present a case of BBS with features of hypogonadism and features such as marked central obesity, retinitis pigmentosa, polydactyly, renal abnormalities and mental ...

The interleukin-1 receptor-associated kinase (IRAK) family comprises critical signaling mediators of the TLR/IL-1R signaling pathways. IRAKs are Ser/Thr kinases. There are 4 members in the vertebrate genome (IRAK1, IRAK2, IRAKM, and IRAK4) and an IRAK homolog, Pelle, in insects. IRAK family members are highly conserved in vertebrates, but the evolutionary relationship between IRAKs in vertebrat...

The NudC family consists of four conserved proteins with representatives in all eukaryotes. The archetypal nudC gene from Aspergillus nidulans is a member of the nud gene family that is involved in the maintenance of nuclear migration. This family also includes nudF, whose human orthologue, Lis1, codes for a protein essential for brain cortex development. Three paralogues of NudC are known in v...

INTRODUCTION One of the key strategies for marketing new drugs to physicians is personal selling by pharmaceutical sales representatives (PSRs). GOAL The aim of this study was to determine which features of PSR's are most valued by Slovenian family physicians (FPs). METHODS We performed a cross-sectional observational postal survey in FPs. We sent the invitation for cooperation in the study...

The interleukin-10 (IL-10) family of cytokines includes IL-10, a number of its viral gene homologs, and eight recently discovered cellular cytokines (IL-19, IL-20, IL-22, IL-24, IL-26, IFN-lambda1, IFN-lambda2, IFN-lambda3). IL-10 is an intercalated dimer consisting of two six-helix bundle domains. Signal transduction occurs when each domain of IL-10 binds to two receptor chains, IL-10R1 and IL...

This paper looks at the present standing of ecommerce in Saudi Arabia, as well as the challenges and strengths of Business to Customers (B2C) electronic commerce. Many studies have been conducted around the world in order to gain a better understanding of the demands, needs and effectiveness of online commerce. A study was undertaken to review the literature identifying the factors influencing ...

Vision based bin picking is increasingly more di cult as the complexity of target objects increases We propose an e cient solution where complex objects are su ciently represented by simple features cues thus invariance to object complexity is established The re gion extraction algorithm utilized in our approach is capable of providing the focus of attention to the simple cues as a trigger towa...