BACKGROUND To explore ways to reduce the overuse of antibiotics for acute respiratory infections (ARIs), we conducted a pilot clustered randomized controlled trial (RCT) to evaluate DECISION+, a training program in shared decision making (SDM) for family physicians (FPs). This pilot project demonstrated the feasibility of conducting a large clustered RCT and showed that DECISION+ reduced the pr...

We consider a multi-armed bandit setting that is inspired by real-world applications in e-commerce. In our setting, there are a few types of users, each with a specific response to the different arms. When a user enters the system, his type is unknown to the decision maker. The decision maker can either treat each user separately ignoring the previously observed users, or can attempt to take ad...

the iranian persian chub is an endemic species of the family cyprinidae known only from few localities in drainages of southern iran. it was originally described in the genus pseudophoxinus as (pseudophoxinus persidis) and then petroleuciscus (as petroleuciscus persidis). in this study, we examined phylogenetic relationships of the iranian persian chubwith other relatives in the family cyprinid...

BACKGROUND In April, 2013, a Suzhou Hospital reported a nitrite intoxication patient in coma as well as 2 family members with the similar symptom 5 days ahead. We investigated the event to identify the cause, source and possible pollution ways of the contamination. METHODS We defined case as any person living in YSHY community who has cyanosis and with at least one of the following symptoms: ...

A family of genes encoding cold-shock proteins, named cspA, cspB, cspC, cspD and cspE, was cloned and sequenced from Lactococcus lactis MG1363. The genes cspA and cspB and the genes cspC and cspD are located in tandem repeats, an organization of csp genes that has never been encountered before. The five genes encode small (7.1-7.6 kDa) proteins with high mutual sequence identities (up to 85%) a...

The staphylococcal enterotoxin-like toxins (SETs) are a family of proteins encoded within the Staphylococcus aureus genome that were identified by their similarity to the well described bacterial superantigens. The first crystal structure of a member of the SET family, SET3, has been determined to 1.9 A (R = 0.205, R(free) = 0.240) and reveals a fold characteristic of the superantigen family bu...

Background: Malnutrition is a great challenge for the public health system. Therefore, this study aimed to study the spatial pattern malnutrition using GIS in the world's countries. Materials and Methods: In this cross-sectional study, secondar...

The organization of Rhodopsin-family G protein-coupled receptors (GPCRs) at the cell surface is controversial. Support both for and against the existence of dimers has been obtained in studies of mostly individual receptors. Here, we use a large-scale comparative study to examine the stoichiometric signatures of 60 receptors expressed by a single human cell line. Using bioluminescence resonance...

The genes belonging to Pumilio gene family of the fission yeast Schizosaccharomyces pombe (S. pombe) were compared with genome information of the several fungi and their functions have been inferred using public-access databases disclosed on the internet websites. The Pumilio-family genes are conserved from yeast to man and have been considered to suppress the expression of other genes by bindi...