نتایج جستجو برای: familial background
تعداد نتایج: 885024 فیلتر نتایج به سال:
Background: Familial history of multiple sclerosis (MS) has been considered as one of the etiologic factors of MS by several studies. It is valuable to combine the results of these studies. The aim of this study is to estimate the pooled prevalence of familial MS in Iran using meta-analysis. Methods: Using relevant keywords, national and international databanks were searched. Considering the si...
BACKGROUND & AIMS Disease outcome has been found to be poorer in familial inflammatory bowel disease (IBD) than in sporadic forms, but assessment of phenotypic concordance in familial IBD provided controversial results. We assessed the concordance for disease type and phenotypic features in IBD families. METHODS Patients with familial IBD were identified from the IBD Spanish database ENEIDA. ...
BACKGROUND The purpose of this study is to follow the familial incidence of non-syndromic or isolated cleft lip, with or without cleft palate (NSCL/P), and to analyze the relationships between the type of NSCL/P in the affected individual and his/her parent, looking at children in the first grade. MATERIAL AND METHODS To investigate the familial incidence of NSCL/P we analyzed the records of ...
Abstract Background Myocarditis is increasingly associated with dilated cardiomyopathy (DCM) and arrhythmogenic (ACM). Purpose The aim of our study was to define if a genetic predisposition exists in cases myocarditis suspicious findings inherited cardiovascular disease (noise) the family. Methods Consecutive patients referred unit from 2010 2021, presentation acute or clinically suspected myoc...
Background Short stature is a manifestation of a wide variety of conditions that some of which may be amenable to timely treatment and a suboptimal growth rate may be an early marker pointing to the cause of growth retardation. This study was conducted to evaluate the diagnostic utility of growth rate in differential diagnosis of children with short stature. Materials and Methods All children ...
Background: Infantile obesity is becoming increasingly recognized as one of the public health problems in Iran. Objective: Obesity charts of a cohort of 317 healthy infants and their parents living in Shiraz (Southern Iran) are presented and the familial pattern of infants’ obesity with that of its parents explored. Methods: An adjusted weight-for-height index was used to develop power type obe...
BACKGROUND Little is known about the factors influencing the future situation of individuals on sickness absence (SA) or disability pension (DP). The aim was to investigate whether being sickness absent is associated with future DP and premature death, and whether such associations can be explained by familial factors. METHODS A sample of 45 734 Swedish twins was followed for 13 years. Cox pr...
در بیماری als نیز بیماران مبتلا دارای تجمعات پروتئینی در جسم سلولی و آکسونهای نورونهای حرکتی بافت عصبی خود می باشند که بطور عمده متشکل از آنزیم سوپراکسید دیسموتاز 1 (sod1) است. جهش در ژن sod1 در 20% از موارد familial als (fals) مشاهده می شود و به عنوان یک عامل مهم در ایجاد این بیماری شناخته می شود. مکانیزم بیماری زایی تجمعات sod1در بیماری fals اگر چه هنوز به طور کامل مشخص نیست اما تغییر در خصوص...
Background and Objectives: Coronary artery diseases (CAD) are the most common cause of death in Iran and worldwide. Myocardial infarction (MI) is a complex multifactorial and the most severe type of CAD. Early onset MI in first degree relatives could be considered as an independent risk factor for CAD. This study was performed to investigate the genetic cause of early onset familial CAD. Cas...
Background and Purpose: Each year, about 50,000 new cases of cancer occur in Iran and the most common being the gastrointestinal (GI) tract (38%). Colorectal cancers account for the 3rd and 4th most prevalent cancers in Iranian men and women, respectively. Since genetic and environmental factors lead to differences in colorectal cancer occurrence in different geographic regions and races, we ...
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