نتایج جستجو برای: f1 generation

تعداد نتایج: 378050  

2000
Rong Jin Alexander G. Hauptmann

The problem of title generation involves finding the essence of a document and expressing it in only a few words. The results of a query to the Informedia Digital Video Library are summarized through an automatically generated title for each retrieved news story. When the document is errorful, as with speech-recognized broadcast news stories, the title creation challenge becomes even greater. W...

Journal: :Birth defects research. Part B, Developmental and reproductive toxicology 2005
George Cruzan Willem D Faber Keith A Johnson Linda S Roberts Juergen Hellwig Jacques Maurissen Melissa J Beck Ann Radovsky Donald G Stump

This study was conducted to assess potential adverse functional and/or morphological effects of styrene on the neurological system in the F2 offspring following F0 and F1 generation whole-body inhalation exposures. Four groups of male and female Crl:CD (SD)IGS BR rats (25/sex/group) were exposed to 0, 50, 150, and 500 ppm styrene for 6 hr daily for at least 70 consecutive days prior to mating f...

2014
Devrah A Arndt Jian Chen Maika Moua Rebecca D Klaper

Several classes of contaminants have been shown to have multigenerational impacts once a parental generation has been exposed. Acute and chronic toxicity are described for several types of nanomaterials in the literature; however, no information is available on the impact of nanomaterials on future generations of organisms after the exposure is removed. In the present study, the authors examine...

2016
Prerna Vohra Kuldeep Singh Khera

In the present study, the effect of oral administration of imidacloprid over three generations on biochemical, histological and physiological alterations in female rats was assessed. Female rats were divided into three groups. Group 1 was control and was given corn oil, group 2 was administered imidacloprid at the rate of 10 mg/kg bw/day, group 3 was administered imidacloprid at the rate of 20 ...

2016
Daniel Lenk Vladimir I Zdravkov Jan-Michael Kehrle Günter Obermeier Aladin Ullrich Roman Morari Hans-Albrecht Krug von Nidda Claus Müller Mikhail Yu Kupriyanov Anatolie S Sidorenko Siegfried Horn Rafael G Deminov Lenar R Tagirov Reinhard Tidecks

BACKGROUND In nanoscale layered S/F1/N/F2/AF heterostructures, the generation of a long-range, odd-in-frequency spin-projection one triplet component of superconductivity, arising at non-collinear alignment of the magnetizations of F1 and F2, exhausts the singlet state. This yields the possibility of a global minimum of the superconducting transition temperature T c, i.e., a superconducting tri...

Journal: :The Journal of Experimental Medicine 1981
U Hurtenbach D H Sachs G M Shearer

Injection of parental spleen cells into unirradiated F1 hybrid mice results in suppression of the potential to generate cytotoxic T lymphocyte (CTL) responses in vitro. In an attempt to protect the F1 mice from immunosuppression, the recipients were injected with antibodies specific for major histocompatibility complex (MHC)-encoded antigens of the F1 mice 24 h before inoculation of the parenta...

2016
Afshan Dean Sander van den Driesche Yili Wang Chris McKinnell Sheila Macpherson Sharon L. Eddie Hazel Kinnell Pablo Hurtado-Gonzalez Tom J. Chambers Kerrie Stevenson Elke Wolfinger Lenka Hrabalkova Ana Calarrao Rosey AL Bayne Casper P. Hagen Rod T. Mitchell Richard A. Anderson Richard M. Sharpe

Analgesics which affect prostaglandin (PG) pathways are used by most pregnant women. As germ cells (GC) undergo developmental and epigenetic changes in fetal life and are PG targets, we investigated if exposure of pregnant rats to analgesics (indomethacin or acetaminophen) affected GC development and reproductive function in resulting offspring (F1) or in the F2 generation. Exposure to either a...

2015
Shayantani Mukherjee Ram Prasad Bora Arieh Warshel

Detailed understanding of the action of biological molecular machines must overcome the challenge of gaining a clear knowledge of the corresponding free-energy landscape. An example for this is the elucidation of the nature of converting chemical energy to torque and work in the rotary molecular motor of F1-ATPase. A major part of the challenge involves understanding the rotary-chemical couplin...

Journal: :Cancer research 1986
P M Pour

Ovarian and testicular tumors were induced in the offspring (F1 generation) of MRC rats that received single or multiple doses of N-nitrosobis(2-oxopropyl)amine on the 14th, 18th, and/or 20th days of pregnancy. The ovarian tumor incidence was significantly higher (46%) in the F1 generation exposed to the carcinogen a single time at the 18th day of gestation, when compared to those exposed at th...

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