To gain insight into how sugar chain processing events modulate endoplasmic reticulum (ER)/proteasomal degradation we looked at human asialoglycoprotein receptor polypeptides H2a and H2b, variants which differ only by an extra pentapeptide (EGHRG) present in H2a. Membrane-bound H2a is a precursor of a soluble secreted form while H2b reaches the plasma membrane. Uncleaved precursor H2a molecules...

Semantic caching is a dynamic caching strategy which deals with not only exact but also inexact similar queries, as the local cache has the capability of analyzing the incoming queries. Therefore, in this manner, each query will be carefully analyzed by the cache manager to identify the part that can be retrieved from cache from the part that needs to be retrieved from the server. This trimming...

We carried out lacerations of 50%, followed by trimming, in ten turkey flexor tendons in vitro and measured the coefficient of friction at the tendon-pulley interface with loads of 200 g and 400 g and in 10 degrees , 30 degrees, 50 degrees and 70 degrees of flexion. Laceration increased the coefficient of friction from 0.12 for the intact tendon to 0.3 at both the test loads. Trimming the lacer...

among the major stressors in poultry that cause suffering and death of chickens. Beak trimming, removal of 1/3 to 1/2 of the beak, is a routine husbandry procedure practiced in the poultry industry, including laying hens, broiler breeders, turkey and ducks, to prevent those undesirable behaviors. However, beak trimming is a painful procedure. There is a considerable body of morphological, neuro...

We demonstrated a vertically coupled microring resonator (VCMRR) filter as an Add/Drop wavelength filter. However, the accuracy of center wavelength was not sufficiently high for dense wavelength division multiplexing (DWDM) systems. Thus, a UV trimming technique using a SiN (n=2.01 at λ=1.55 μm) ring core was previously developed. Although a wide center wavelength trimming range of −12.1 nm an...

Trimmed Linear moments (TL-moments) are natural generalization of Lmoments that do not require the mean of the underlying distribution to exist. It is known that the sample TL-moments is unbiased estimators to corresponding population TL-moment. Since different choices for the amount of trimming give different variances for the estimators it is important to choose the estimator that has less va...

Recent work introduced an effective method for extraction of reduced unsatisfiable cores of CNF formulas as a by-product of validation of clausal proofs emitted by conflict-driven clause learning SAT solvers. In this paper, we demonstrate that this method for trimming CNF formulas can also benefit state-of-the-art tools for the computation of a Minimal Unsatisfiable Subformula (MUS). Furthermor...

We have studied the effects of propofol, as the sole agent, at blood concentrations of 1-10 micrograms ml-1, on the first 100 ms of the auditory evoked response (AER) in 41 women before gynaecological surgery. AER were recorded with the patients awake and then after 30 min of one of seven stepped infusion regimens. Each patient was studied at only one blood concentration. The recordings were ed...