This article explores the application of two-eyed seeing in the first year of a three-year study about the effectiveness of cultural interventions in First Nations alcohol and drug treatment in Canada. Two-eyed seeing is recognized by Canada's major health research funder as a starting point for bringing together the strengths of Indigenous and Western ways of knowing. With the aim of developin...

Pleistocene glacial cycles are thought to have played a major role in the diversification of temperate and boreal species of North American birds. Given that coalescence times between sister taxa typically range from 0.1 to 2.0 Myr, it has been assumed that diversification occurred as populations were isolated in refugia over long periods of time, probably spanning one to several full glacial c...

Sash (Wsh), a viable and fully fertile allele of the dominant spotting (W) locus (Lyon & Glenister, 1982) has been used in a modified test system to investigate the site of gene expression at the pink-eyed dilution (p) locus. Reciprocal recombinant epidermal@dermal skin grafts were constructed from 13-day embryonic skin of p and Wsh homozygotes. Thus in the reciprocal experiments pink-eyed dilu...

An importance sampling simulation technique is used to estimate the bit-error rate (BER) of a symbol-by-symbol trelliscoded modulation (TCM) decoder/equalizer proposed for digital microwave radio applications. To evaluate the performance at a BER smaller than 10 , we investigate a randomized bias technique previously developed by the authors. To properly select the bias vectors, the asymptotic ...

Two congenic strains of RCS rats, RCS-p/+ and RCS-c, have been developed that differ from the parental strain at genetic loci affecting pigmentation. Inbred RCS rats are pink-eyed, while RCS-p/+ rats produce segregating litters of pink-eyed (p/p) and black-eyed (p/+) offspring, and RCS-c rats are albinos. All the strains are homozygous for the mutant form of the retinal dystrophy gene. The blac...

Human embryonic stem cell (hESC)-derived retinal pigment epithelial (RPE) cells could replace lost tissue in geographic atrophy (GA) but efficacy has yet to be demonstrated in a large-eyed model. Also, production of hESC-RPE has not yet been achieved in a xeno-free and defined manner, which is critical for clinical compliance and reduced immunogenicity. Here we describe an effective differentia...

Otrthogonal Frequency Division Multiplex (OFDM) system performance remains acceptable under timing synchronisation errors as long as the start of each symbol is determined to lie within a certain length into the Cyclie Prefix (CP). The Schmidl and Cox Algorithm (SCA) is quite robust in estimating the timing and frequency offset synchronisation for systems with large OFDM symbol lengths. It uses...

The present study was conducted to evaluate the effect of different extenders and storage periods on motility and fertilizing ability of short-term stored grass carp sperm during spawning season. Sperm was collected from anesthesized males by the abdominal massage method. Having determined the main spermatological properties, the pooled ejaculates were diluted with 3 different extenders at a ra...