A cylindrical elastomer tube can stay in an everted state without any external forces. If the thickness of the tube is small, the everted tube, except for the regions close to the free ends of the tube, maintains a cylindrical shape, and if the thickness is larger than a critical value, the cross-section of the everted tube becomes noncircular, which is caused by mechanical instability. Althoug...

The commensal microbiota impacts specific immune cell populations and their functions at peripheral sites, such as gut mucosal tissues. However, it remains unknown whether gut microbiota control immunity through regulation of hematopoiesis at primary immune sites. We reveal that germ-free mice display reduced proportions and differentiation potential of specific myeloid cell progenitors of both...

BACKGROUND Solid lipid nanoparticles (SLN), novel drug delivery carriers, can be utilized in enhancing both intestinal permeability and dissolution of poorly absorbed drugs. The aim of this work was to enhance the intestinal permeability of sulpiride by loading into SLN. METHODS A unique ultrasonic melt-emulsification method with minimum stress conditions was used for the preparation of SLN. ...

INGS MESON. Hexose transport by hamster intestine in vitro. Am. J. Physiol. 203(2): 237-240. Ig62.-The ability of everted sacs of hamster intestine to concentrate 18 glycosides and 5-deoxyglucose was determined. It was concluded that most of the glycosides were actively transported, but the nature of the aglycone is an important determinant in the extent of transport. A pyranose configuration i...

I . The effects of dietary antibiotics (penicillin, neomycin or terramycin) on the absorption of D-glucose, D-galactose, L-arginine or L-histidine by the mouse were investigated by using sacs of entire everted ileum. 2. Compared with the controls, there was generally an increased absorption of all these solutes. Tissue uptake of the solutes remained unaltered. The inward movement of water into ...

[14C]Taurocholate was orally administered to rats together with a definite amount of either casein- or soy protein-based diet and its postprandial movement along the digestive tract was investigated. A difference was observed between both dietary groups in intraluminal transit as well as mucosal accumulation of [14C]taurocholate in the ileum; namely the soy protein intake led to a decrease in t...

A new genus and species of nasutitermitine termites are described and illustrated, based on soldier and worker characters. Sinqasapatermesgen. n., can be distinguished from all other nasutitermitine genera by its singular worker gut coiling and enteric valve characters: distal margin of the enteric valve not everted into the paunch but bending towards the ileum, that is, directed against the fl...

SCHACHTER, DAVID AND SAMUEL M. ROSEN. Active transport of G-2 45 by the small intestine and its dependence on vitamin 13. Am. J. Physiol. r g6(2): 357-362. I g5g.-Everted gut-sacs prepared from segments of the proximal small intestine of young rabbits, rats and guinea pigs transport Ca45 in vitro from the mucosal to the serosal surfaces against concentration gradients. The active transport mech...