نتایج جستجو برای: eudragit rspo

تعداد نتایج: 918  

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2011
L Saerens L Dierickx B Lenain C Vervaet J P Remon T De Beer

The aim of this study was to evaluate the suitability of Raman spectroscopy as a Process Analytical Technology (PAT) tool for the in-line determination of the active pharmaceutical ingredient (API) concentration and the polymer-drug solid state during a pharmaceutical hot-melt extrusion process. For in-line API quantification, different metoprolol tartrate (MPT)--Eudragit® RL PO mixtures, conta...

Journal: :Advanced pharmaceutical bulletin 2013
Abbas Akhgari Zohreh Heshmati Behzad Sharif Makhmalzadeh

PURPOSE The objective of this study was to prepare a suitable form of nanofiber for indomethacin using polymers Eudragit RS100 (ERS) and Eudragit S100 (ES) and to evaluate the effect of some variables on the characteristics of resulted electrospunnanofibers. METHODS Electrospinning process was used for preparation of nanofibers. Different solutions of combinations of ERS, ES and indomethacin ...

Journal: :International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration 2023

The agricultural sector is one of the crucial sectors in Indonesia, which primary source food and economic growth. role this can still be increased if appropriately managed. In today's international trade, sustainability most important things to maintain, embodied Roundtable on Sustainable Palm Oil (RSPO) certification. Corporate Social Responsibility (CSR) policies used as strategies carried o...

Journal: :Journal of pharmaceutical sciences 2016
David S Jones Yiwei Tian Shu Li Tao Yu Osama A Abu-Diak Gavin P Andrews

The objective of this study was to determine if a high Tg polymer (Eudragit(®) S100) could be used to stabilize amorphous domains of polyethylene oxide (PEO) and hence improve the stability of binary polymer systems containing celecoxib (CX). We propose a novel method of stabilizing the amorphous PEO solid dispersion through inclusion of a miscible, high Tg polymer, namely, that can form strong...

2014
Tae-Hyun Kim Jeong-A Lee Soo-Jin Choi Jae-Min Oh

We have successfully prepared layered double hydroxide (LDH) nanomaterials containing calcium and aluminum ions in the framework (CaAl-LDH). The surface of CaAl-LDH was coated with enteric polymer, Eudragit®L 100 in order to protect nanomaterials from fast dissolution under gastric condition of pH 1.2. The X-ray diffraction patterns, Fourier transform infrared spectroscopy, scanning electron an...

2013

Objective: Azelnidipine, a long-acting dihydropyridine based calcium channel blocker, on oral administration, the drug undergoes extensive first pass metabolism. Delivery of azelnidipine (AZP) via transdermal route would minimize some of the deficiencies associated with the oral delivery and increase the bioavailability of the drug. In the present study, is to investigate the development and ev...

Journal: :Molecules 2018
Vincenzo De Leo Francesco Milano Erminia Mancini Roberto Comparelli Livia Giotta Angelo Nacci Francesco Longobardi Antonella Garbetta Angela Agostiano Lucia Catucci

The present study aimed to develop and optimize liposome formulation for the colonic delivery of biologically active compounds. A strategy to facilitate such targeting is to formulate liposomes with a polymer coating sensitive to the pH shifts in the gastrointestinal tract. To this end, liposomes encapsulating curcumin-chosen as the biologically active compound model-and coated with the pH-resp...

2014
Mohammad Ali Dabbagh Behzad Taghipour

Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissolution be...

2007
Golam Kibria

The aim of the present study is to investigate the effect of Ammonio Methacrylate Copolymer Type B (Eudragit RS 30 D) on the release kinetics study of diclofenac sodium form coated pellets. The effect of the incorporation of xanthan gum into the coating formulation was also the goal of this study. Eudragit RS 30 D and xanthan gum was added into the formulation at 5:1 ratio. Different percent of...

2015
Zahra Jafariazar Nasim Jamalinia Fatemeh Ghorbani-Bidkorbeh Seyed Alireza Mortazavi

Diclofenac sodium as ophthalmic dosage form is used for the treatment of the pain, swelling and redness of patients' eyes recovering from cataract surgery; however, it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled...

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