Unsustainable energy consumption is a systemic problem facing society that requires technical and social innovations and changes. We argue for understanding and using end-user developments as not just another design principle but as a socio-technical intervention to help people make better decisions as they work to solve such systemic problems. We further explore two established EUD frameworks,...

Sustainable and equitable urban development (S&EUD) is vital to promote healthy lives well-being for all ages. Recognizing equity as core essential ensure that cities are inclusive, safe, resilient, sustainable. The aim of this study was identify assess the elements sustainability in exemplary bright spots using ACE Framework United Nations’ 5 Ps Development. A content analysis process perf...

This article examines Aristotle's method for defining the concept of happiness in his Eudemian and Nicomachean ethics . In particular, draws attention to a methodological passage ( Eth. Eud. 1.6 1216b26–35), which he claims that ‘If we start from what is truly yet not clearly spoken, clarity will be won as make progress’. expression comes Plato's Statesman 275a 281d. Aristotle then seems adopt ...

PURPOSE The impact of multileaf collimator (MLC) design and IMRT technique on plan quality and delivery improvements for head-and-neck and meningioma patients is compared in a planning study. MATERIAL AND METHODS Ten previously treated patients (5 head-and-neck, 5 meningioma) were re-planned for step-and-shoot IMRT (ssIMRT), sliding window IMRT (dMLC) and VMAT using the MLCi2 without (-) and ...

Compared with step-and-shoot intensity-modulated radiotherapy (sIMRT) and tomotherapy, volumetric-modulated arc therapy (VMAT) allows additional arc configurations in treatment planning and noncoplanar (NC) delivery. This study was first to compare VMAT planning with sIMRT planning, and the second to evaluate the toxicity of coplanar (C)/NC-VMAT treatment in patients with hepatocellular carcino...

Sustained release (SR) dosage forms enable prolonged and continuous deposition of the drug in the gastrointestinal (GI) tract and improve the bioavailability of medications characterized by a narrow absorption window. In this study, a new strategy is proposed for the development of SR dosage forms for theophylline (TPH). Design of the delivery system was based on a sustained release formulation...

Spatial accuracy in extracranial radiosurgery is affected by organ motion. Motion tracking systems may be able to avoid PTV enlargement while preserving treatment times, however special attention is needed when fiducial markers are used to identify the target can move with respect to organs at risk (OARs). Ten patients treated by means of the Synchrony system were taken into account. Sparing of...

The purpose of this study was to compare dosimetric and radiobiological parameters of treatment plans using coplanar and noncoplanar beam arrangements in patients with fronto-temporal high-grade glioma (HGG) generated for intensity-modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT). Ten cases of HGG overlapping the optic apparatus were selected. Four separate plans were cr...

This study was to assess the Capri applicator for patients with endometrial cancer undergoing high-radiation dose treatments following external-beam radiation therapy. The Capri applicator is an inflatable vaginal cylinder with multiple channels. It is used to tailor the dose distribution to an asymmetric vaginal disease, and better spare organs at risk. Five patients with high-risk endometrial...