Endobronchial metastases from extrapulmonary neoplasms are rare events and there is no report on the metastasis originating from esophageal cancer. Basaloid squamous carcinoma of the esophagus is a rare histologic type, which is known as biologically aggressive phenotype. We describe a rare case of metachronous endotracheal metastasis originating from esophageal basaloid squamous carcinoma. A 7...

Human esophageal cancer is one of the most common causes of cancer death in China. Tumor recurrence and metastasis are the main reasons for the failure in cancer treatments. Increasing evidences indicated that cancer stem cell (CSC) are thought to be responsible for tumor initiation and progression. Therefore, therapies targeting cancer stem cells offer a promising strategy for cancer treatment...

OBJECTIVE Mortality due to esophageal adenocarcinoma has risen markedly, but the molecular mechanisms underlying this carcinogenesis are still incompletely understood. Findings from loss of heterozygosity (LOH) studies have suggested that the long arm of chromosome 4 might harbor tumor suppressor genes relevant to esophageal adenocarcinoma. METHODS We performed LOH analysis of 4q in esophagea...

CD97 expression is related closely to the dedifferentiation and tumor stage in thyroid carcinomas. We systematically examined the role of CD97 and its closest relative, EMR2, in normal and malignant gastric, esophageal, and pancreatic tissue. The normal tissues were EMR2-, whereas CD97 was expressed slightly in the parietal cells of gastric mucosa and in exocrine pancreatic cells. Interestingly...

Esophageal cancer is characterized by rapid clinical progression and poor prognosis, due to early-stage invasion of adjacent tissues and metastasis. Tissue factor pathway inhibitor-2 (TFPI-2) has been implicated as a metastasis-associated gene in many types of tumors. Here we describe the potential involvement of TFPI-2 in the development of esophageal carcinoma. Western blotting revealed that ...

INTRODUCTION Esophageal fibrovascular polyps are rare, benign, intraluminal, submucosal tumor-like lesions, characterized by pedunculated masses which can demonstrate enormous growth. The most frequent symptoms are dysphagia, vomiting and weight loss. Fibrovascular polyps with long stalks can regurgitate into the airways and cause asphyxia. Esophageal inflammatory pseudotumor is extremely rare ...

Objective: To analyze the relationship between TIGIT and clinical features of Esophageal Squamous Cell Carcinoma, we use transcriptomic data from TCGA database, to investigate immune microenvironment provide a basis for improving treatment strategy prognosis patients with Carcinoma. Methods: RNA sequencing corresponding cancer tissues were obtained database carcinoma, Carcinoma tissues, paraneo...

Abstract Introduction. Esophageal cancer is one of the most aggressive visceral tumors with increasing frequency and poor prognosis. Differences in survival between patients same clinical tumor stage necessitate searching for additional prognostic markers to help identify at high risk recurrence, metastasis or death. The aim study was assess significance length on after esophageal resection ope...