Introduction: The relationship between Ηelicobacter pylori (hp) gastritis, the most common infection worldwide and Gastroesophageal Reflux Disease (GERD), a major health problem in Western Countries, remains controversial. AIM: To investigate the association between hp infection and GERD and the impact of hp eradication on esophageal acid exposure and esophageal motility in hp-positive patients...

BACKGROUND In our previous case report of circumferential mucosal resection for short-segment Barrett's esophagus with high-grade dysplasia, symptoms of gastro-esophageal reflux disease (GERD) were significantly improved. This observation suggests that anti-reflux mucosectomy (ARMS) could represent an effective anti-reflux procedure, with the advantage that no artificial devices or prostheses w...

Background/Aims Evaluation of esophageal clearance by orange juice swallowing could be useful to identify different categories of gastroesophageal reflux disease. We determined whether a juice test at the beginning of esophageal pH monitoring can identify nonerosive reflux disease (NERD) among heartburn patients. Methods Multiple swallows of orange juice (pH 3) were performed at the beginning...

Multichannel intraluminal impedance is a relatively new technology that allows detection of bolus movement in the gastrointestinal tract without the use of radiation. In clinical applications it is combined with manometry, allowing a better evaluation of the functional characteristics (ie, bolus transit) of esophageal motility abnormalities. When combined with pH monitoring, it provides more co...

BACKGROUND Nighttime reflux has been shown to be associated with esophageal mucosal injury, complications, and extra-esophageal manifestations. However, few studies have assessed the impact of gastroesophageal reflux on reported quality of sleep and quality of sleep on gastroesophageal reflux. AIMS The aims of this study were (1) to determine the correlation between the severity of gastroesop...

Aim: Esophagus is the most frequently involved gastrointestinal segment in systemic sclerosis (SS). Gastroesophageal reflux, which occurs with motility disorder caused by esophageal involvement, has an important place course of disease due to many local and complications. In this study, we investigated demographic features, endoscopic, manometric, 24-hour pH monitoring findings patients SS.&#x0...

BACKGROUND Patients with gastroesophageal reflux disease (GERD) are treated with proton pump inhibitors (PPIs). Those that do not achieve symptom relief, or non-responders, usually undergo esophageal pH monitoring off PPIs in order to confirm the presence of GERD. AIMS To assess the efficacy of the reverse-PPI trial in evaluating the presence of GERD or its recurrence rates, as well as to ide...

OBJECTIVE To report the prevalence of esophagitis in patients with pH-documented laryngopharyngeal reflux. STUDY DESIGN Prospective study of 58 consecutive patients with documented laryngopharyngeal reflux, all of whom underwent transnasal esophagoscopy as part of their reflux evaluations. METHODS All patients with a diagnosis of laryngopharyngeal reflux confirmed by abnormal pharyngeal pH ...

INTRODUCTION The conventional 24-hour pH monitoring is the gold standard for the diagnosis of gastro-esophageal reflux (GER), a possible cause of Apparent Life Threatening Episodes (ALTE). However, multichannel intraluminal impedance (MII) may provide advantages. OBJECTIVES Comparison of the results of MII and pH monitoring in patients undergoing MII-pH monitoring in the 3-year study period b...