This issue of Endoscopy focuses on total endo− scopic eradication of Barrett’s esophagus, a con− dition described by the Australian surgeon Nor− man Rupert Barrett in 1950 [1]. This paper con− siders methodological aspects of studies of abla− tive therapies for Barrett’s esophagus, and how the choices made by investigators with respect to study methodology and candidate selection might impact t...

BACKGROUND There are very few prospective follow-up studies of Barrett esophagus (BE) cohorts assessing the risk of extraesophageal cancer incidence or mortality. Such studies are necessary in order to understand the overall risks of cancer and death experienced by patients with BE. METHODS A cohort of 502 patients with BE were identified at Leeds General Infirmary, England. Mortality and can...

Esophageal cancer is the fourth cancer of digestive system that constitutes two up to five percent of all identified malignancies (1). One of the main characteristics of this lethal disease is its specific geographical distribution. For instance, its incidence has been reported to be 3/100,000 in Europe and USA (2). However, this is in some parts of central Asia, which is known as esophageal ca...

introduction: caustic ingestion is responsible for a spectrum of upper gastrointestinal tract injury from self-limited to perforation. this study conducted to evaluate clinical characteristics as well as surgical outcomes in patients with caustic ingestion.   materials and methods: between nov1993 to march 2011, 14 adults with a clinical evidence of corrosive ingestion were admitted into our in...

Data from recent studies cast doubt on former recommendations on diagnosis and management of Barrett's esophagus. Based on latest research findings several Gastroenterological Associations actualized their guidelines and international experts compiled consensus statements as practical help for clinicians. In this review we discuss recent trials and their impact on clinical practice, current rec...

 Abstract Background: Esophageal replacement is indicated in certain circumstances including long gap esophageal atresia, severe strictures due to gastro-esophageal reflux (GER) and caustic burns. We analyzed our results of 18 patients who underwent esophageal replacement in our university hospital. Methods: We reviewed esophageal replacements carried out in our department between June 1996 and...

BUMC PROCEEDINGS 2003;16:280–284 Although esophageal carcinoma is not the most common tumor—it accounts for only 5% of all gastrointestinal tumors and 1% of all new tumors—it has nearly a 1:1 mortality ratio: each year there are 14,000 new cases and 13,000 related deaths in the USA. Men have esophageal carcinoma 3 to 5 times more often than women, and black men are 3 times more likely than whit...

With advancements in the development of flexible endoscopes and endoscopic devices increased demand for minimally invasive treatments, indications therapeutic endoscopy have been expanded. Methods treatment used tissue removal, hemostasis, dilatation are as follows. Endoscopic submucosal dissection (ESD) is considered gold standard curative method removal gastrointestinal node-negative neoplasm...