We report seven early gastric cancers in five patients, which arose in the reconstructed gastric tube after radical resection for esophageal cancer. Four of them occurred in the middle gastric tube and three in the distal gastric tube. Three of 5 cases were reconstructed via the retromediastinal route and two via the presternal route. They all were diagnosed by follow-up endoscopy from 8 months...

The pathophysiology of esophageal and gastric disorders is complicated and broad and includes iatrogenic, structural, inflammatory, neuromuscular, neoplastic, and infectious causes. Symptoms can be nonspecific and are often initially attributed to cardiac or respiratory causes. These disorders have both acute and chronic presentations that require different approaches to diagnosis and managemen...

BACKGROUND From March 1986 through May 1991, we conducted a randomized nutritional intervention trial, the General Population Trial, in Linxian, China, a region with epidemic rates of squamous esophageal and adenomatous gastric cardia cancers. We found that participants who received selenium, beta-carotene, and vitamin E had significantly lower cancer mortality rates than those who did not. In ...

OBJECTIVE To determine the clinical serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9), individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. METHODS The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating ...

Proton pump inhibitors reduce gastric acid secretion and are commonly utilized in the management of gastroesophageal reflux disease across all ages. Yet a decrease in lower esophageal sphincter tone has been reported in vitro in rats through an unknown mechanism; however, their effect on the gastroesophageal muscle tone early in life was never studied. Hypothesizing that proton pump inhibitors ...

introduction: gastric drainage disorder is one of the complications of gastric pull-up and esophagectomy after surgery which might lead to esophageal cancer and benign strictures. the aim of this study was to determine the role of pyloromyotomy on gastric drainage. materials and methods: in this prospective randomized controlled clinical trial study, we studied 51 patients in two matched groups...

introduction: it has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of h2s, but till now the effect of duodenal acidification on gastric h2s release has not been investigated. therefore, the present study designed to evaluate the effects of duodenal acidification on gastric h2s release and level of mrna expression of cystath...

Article: The Effect of abdominal visceral fat, circulating inflammatory cytokines, and leptin levels on reflux esophagitis CC This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided th...

INTRODUCTION Achalasia cardia is characterized by failure of the lower esophageal sphincter to relax in response to swallowing and by an absence of peristalsis in the esophageal body. Absence of a gastric air bubble is a well known radiological finding. Pneumatic balloon dilatation results in reappearance of the gastric bubble. CASE PRESENTATION We report the case of a 43-year-old Indian man ...