Achalasia is generally accepted as a condition associated with an increased risk for developing esophageal squamous cell carcinoma. In our paper, we introduced an achalasia patient combined with synchronous early esophageal neoplasms. We performed a combination of concurrent endoscopic submucosal dissection (ESD) and peroral endoscopic myotomy (POEM). No complications other than postoperative p...

BACKGROUND/AIMS The motility change after peroral endoscopic myotomy (POEM) in achalasia is currently focused on lower esophageal sphincter (LES). This study aims to investigate the correlation of motility response between distal and proximal esophagus after POEM. METHODS A total of 32 achalasia patients who received POEM and high-resolution manometry (HRM) were included for analysis. Eckardt...

Achalasia is a primary esophageal motility disorder characterized by the absence of primary peristalsis and a failure of the lower esophageal sphincter to relax, resulting in a dilated esophagus. Dysphagia is the classic and most common symptom. Respiratory obstruction due to tracheal compression caused by a massively dilated esophagus is a very rare but fatal complication. Herein, we report a ...

Achalasia is a disorder characterized by aperistalsis of the esophageal body and impaired relaxation of the lower esophageal sphincter. Dysphagia and regurgitation of undigested, retained food or accumulated saliva are common presenting symptoms. Recurrent aspiration pneumonia may also occur particularly in older patients [1]. Patients with achalasia are clearly at a high risk for aspiration du...

BACKGROUND Achalasia is an esophageal motility disorder, of unknown cause, which results in increased lower esophageal sphincter tone and symptoms of difficulty swallowing. Current major therapeutic options include laparoscopic Heller myotomy (LHM) and pneumatic dilation (PD). We undertake a systematic review comparing the efficacy and safety of these 2 treatments in the treatment of esophageal...

HYPOTHESIS Laparoscopic Heller myotomy with anterior hemifundoplication is the surgical procedure of choice for the treatment of esophageal achalasia. Specific factors, eg, severity of esophageal body deformity, might affect postoperative outcome. DESIGN Prospective case-control study. SETTING Academic referral center for gastrointestinal tract motility disorders. PATIENTS Twenty-nine pat...

BACKGROUND Dynamic esophageal scintigraphy has been proven as an efficient technique of diagnosis of esophageal dysmotility. METHODS The authors monitored the transit velocity, anti-peristalsis and the retention of radioactivity in the esophagus by dynamic esophageal scintigraphy in a group of 50 patients (37 control patients and 13 patients with achalasia). RESULTS They found a significant...

Achalasia is a rare motor disorder of the esophageal smooth muscle that occurs in 1 in 100,000 individuals. The disorder occurs at the level of the lower esophageal sphincter which does not relax normally with swallowing [1]. This leads to progressive dysphagia, chest pain and regurgitation of undigested foods and liquids. The underlying abnormality is loss of intramural neurons and is usually ...