Esophageal perforation continues to be a difficult diagnostic and management problem. Recommendations regarding treatment remain controversial. 17 patients with perforation of the esophagus were retrospectively reviewed at the Thoracic Surgery Unit of Imam Khomeini Hospital between 1981 and 1992. The majority of the injuries involved the thoracic esophagus (10 or 59%), followed by the cerv...

RATIONALE The deep-rooted pathogenesis of the human papilloma virus (HPV) infection is still uncertain and argumentative. As we know, a lot of cases of esophageal infections, such as esophageal squamous cell carcinoma (ESCC) and esophageal squamous papilloma (ESP), associated with HPV are reported. However, primary esophageal ulcer infection associated with HPV is unusual. PATIENT CONCERNS Th...

Treatment of esophageal stricture is important because esophageal stricture reduces the quality of life of patients by increasing their risks of dysphagia, weight loss, nutritional imbalance, and pneumonia due to aspiration. Esophageal stricture is mainly classified as benign or malignant esophageal stricture, and may occur as fibrous production and collagen deposition due to chronic ulceration...

esophageal squamous cell carcinoma is a rather common cancer in northern iran. incidence of adenocarcinoma of esophagus has an increasing trend in iran. co-existence of both cancers in one patient is very rare. we report a middle age woman from northern iran with a typical presentation of esophageal cancer, who was found to have a dual esophageal cancer. the disease was found in the advanced st...

Introduction: Early diagnosis and appropriate treatment is required in esophageal cancer due to its invasive nature. The aim of this study was to evaluate early post-esophagectomy complications in patients with esophageal cancer who received neoadjuvant chemoradiotherapy (NACR).   Materials and Methods: This randomized clinical trial was carried out between 2009 and 2011. Patients with lower-th...

After surgical correction of esophageal atresia with or without tracheoesophageal fistula, esophageal body motility dysfunction has been reported in nearly all patients. Using high-resolution esophageal manometry before surgical repair in 2 children with isolated tracheoesophageal fistula, we sought to determine whether dysmotility was present before any surgical insult to test the hypothesis t...

The best-defined primary esophageal motor disorder is achalasia. However, symptoms such as dysphagia, regurgitation and chest pain can be caused by other esophageal motility disorders. The Chicago classification introduced new manometric parameters and better defined esophageal motility disorders. Motility disorders beyond achalasia with the current classification are: esophagogastric junction ...

BACKGROUND The PTCH expression level in esophageal squamous cell carcinoma (SCC) was examined. MATERIALS AND METHODS To test whether PTCH can serve as a candidate marker for esophageal SCC, a quantitative reverse transcription (RT) -PCR for the PTCH gene was performed and the possible relationship between PTCH gene expression levels and clinicopathological findings in esophageal SCC was evalu...

Cardiac and esophageal causes of atypical pain in the chest are often a difficult diagnostic problem. The pain is considered atypical because of its unusual distribution or unusual precipitating and relieving factors. One hundred and five patients with such pain were evaluated by complete esophageal and cardiac investigation. Based on the results of the investigations, 43 patients were found to...