نتایج جستجو برای: escape mutant

تعداد نتایج: 159232  

Journal: :iranian biomedical journal 0
فاطمه کمال fatemeh kamal هادی مهرگان hadi mehrgan مهناز مظاهری اسدی mahnaz mazaheri assadi سیدعلی رضا مرتضوی seyed alireza mortazavi

xanthan gum is a microbial polysaccharide of great commercial importance as it has unusual rheological properties in solution and consequent range of applications. in this study, a series of mutants were isolated from xanthomonas campestris ptcc 1473 by ethyl methanesulfonate mutagenesis. the polysaccharide yield of one mutant, xc1473e2, was 30% better than that of the parent strain. it also sh...

Journal: :Journal of virology 2014
Pankaj Pal Julie M Fox David W Hawman Yan-Jang S Huang Ilhem Messaoudi Craig Kreklywich Michael Denton Alfred W Legasse Patricia P Smith Syd Johnson Michael K Axthelm Dana L Vanlandingham Daniel N Streblow Stephen Higgs Thomas E Morrison Michael S Diamond

UNLABELLED Chikungunya virus (CHIKV) is a reemerging mosquito-transmitted alphavirus that causes epidemics of debilitating polyarthritis in humans. A prior study identified two anti-CHIKV monoclonal antibodies ([MAbs] CHK-152 and CHK-166) against the E2 and E1 structural proteins, which had therapeutic efficacy in immunocompetent and immunocompromised mice. Combination MAb therapy was required ...

Journal: :Genetics 2015
Peter Ashcroft Franziska Michor Tobias Galla

Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential acquisition of (epi)genetic alterations has been the topic of much investigation. The phenomenon of stochastic tunneling, where an intermediate mutant in a sequence does not reach fixation in a population before gener...

Journal: :iranian journal of biotechnology 2016
muhammad azmat ullah khan ahmad ali shahid abdul qayyum rao kamran shehzad bajwa adnan muzaffar

background: gossypium arboreum is resistant to cotton leaf curl burewala virus and its cognate cotton leaf curl multan betasatellite (clcubuv and clcumb). however, the g. arboreum wax deficient mutant (gawm3) is susceptible to clcuv. therefore, epicuticular wax was characterized both quantitatively and qualitatively for its role as physical barrier against whitefly mediated viral transmission a...

Introduction: Profilin1 (PFN1) is a ubiquitously expressed protein known for its function as a regulator of actin polymerization and dynamics. A recent discovery linked mutant PFN1 to Amyotrophic Lateral Sclerosis (ALS), which is a fatal and progressive motor neuron disease. We have also demonstrated that Gly118Val mutation in PFN1 is a cause of ALS, and the formation of aggregates containing m...

The dynamical behaviour of the forced escape oscillator, which depends on the parameter values we considered, have been studied numerically using the techniques of phase portraits and Poincar'{e} sections. Also, we employed perturbation methods such as Lindstedt's method to obtain the frequency-amplitude relation of escape oscillator.

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