Artificial sweeteners are man-made substitutes for diet that needs low sugars or caloric intake. Recent studies have shown AS consumption is possibly associated with metabolic disturbances and intestinal flora disturbances. Erythritol a kind of 4-carbon sugar substitute in the form alcohol, which may contribute to prevention gingivitis by inhibit biofilm formation oral bacteria. Despite these s...

The title compound, C(17)H(27)BrO(5), DEB, is a derivative of artemisinin which is used in malara therapy. The OR-group at C12 is cis to the CH(3)-group at C11 and axially oriented on ring D which has a chair conformation. The crystal packing is stabilized by several weak inter-molecular C-H⋯O inter-actions, which combine to form a C-H-O bonded network parallel to (001).

Tn10 transposes nonreplicatively. Staged in vitro reactions demonstrate that a Tn10 synaptic complex can become committed to a particular target DNA molecule via a noncovalent interaction in the absence of strand transfer. Commitment occurs only after double-strand cleavage at both transposon ends (in "double-end break" [DEB] complexes). Stable noncovalent DEB-target DNA cocomplexes can be dete...

Biotechnology Centre, Cranf ield University, Cranfield, Bedford MK43 OAL, UK The entomopathogenic fungi Beauveria bassiana, Metarhizium anisopliae and Paecilomyces farinosus were cultured on solid agar media containing different carbohydrate components (glycerol, glucose, trehalose or starch) at concentrations of < 142.7 g added carbon I-1 for 30 d at 25 "C. The water activity (a, ) of the medi...

The title compound, C(16)H(12)N(2)O, was accidentally synthesized by the reaction of 4-(bromo-meth-yl)benzonitrile and penta-erythritol. The dihedral angle between the benzene rings is 57.39 (9)°. In the crystal structure, mol-ecules are linked by inter-molecular C-H⋯N hydrogen-bonding inter-actions to form chains running parallel to the b axis.

In order to better assess non-nutritive sweetener (NNS) consumption, measurement tools with greater utility are needed. The objective of this investigation is to determine the reproducibility and validity of a newly developed NNS food frequency questionnaire (NNS-FFQ) that measures five types of NNS (saccharin, aspartame, acesulfame potassium, sucralose and erythritol). Adult participants (n = ...

PURPOSE To evaluate the efficacy of osmoprotectants on prevention and treatment of dry eye in a murine model. METHODS Dry eye was induced in mice by using an intelligently controlled environmental system (ICES). Osmoprotectants betaine, L-carnitine, erythritol, or vehicle (PBS) were topically administered to eyes four times daily following two schedules: schedule 1 (modeling prevention): dosi...