The study aimed to investigate the phenotypic and genotypic identification of in vitro antimicrobial susceptibility of 21 Staphylococci (10 Staphylococcus aureus and 11 Coagulase Negative Staphylococci) isolated from bovine mastitis to 12 antimicrobial drugs frequently using in veterinary medicine in Algeria. Isolates of staphylococci from bovine mastitis were tested for antibiotics with disc-d...

The synthesis of heterologous proteins in Lactococcus lactis is strongly influenced by the promoter selected for the expression. The nisin A promoter is commonly used for induced expression of proteins in L. lactis, whereas few constitutive promoters (P45 and the weaker P32) have been used for protein expression studies. In this study, eight different putative strong constitutive promoters were...

The in vitro antibacterial activities of oral cephem antibiotics and ketolide telithromycin against major respiratory pathogens possessing beta-lactam-resistant mutations (within the pbp gene) and/or macrolide-resistant genes (erm and mef) were examined in clinical isolates collected at 66 institutes in all over the Japan between 2002 and 2003. Telithromycin showed the strongest antibacterial a...

Methicillin-resistant Staphylococcus aureus (MRSA) has been listed by the World Health Organization as a priority antibiotic-resistant nosocomial pathogen in urgent need of new antimicrobials [1]. Plasmids are key factor pathology and epidemiology MRSA isolates play important roles their evolution. In our on-going efforts to better understand genetic background molecular from Terengganu, Malays...

Erythromycin and clindamycin are major alternatives to βlactam antibiotics. Bacterial resistance to macrolide and lincosamide antibiotics is increasing worldwide. Erm genes express either constitutive macrolide, lincosamide streptogramin B resistance phenotype (cMLSB) or inducible phenotype (iMLSB) and msrA gene expresses (MSB) phenotype. The aim of this study was to determine the frequency of ...

(1) Background: The uncontrolled increase in pollutants the aquatic environment results antibiotic-resistant bacteria and antibiotic resistance genes (ARBs ARGs). overuse misuse of antibiotics is also a crucial factor for public health. (2) Methods: In this study, presence ARBs 24 from eight different classes were evaluated addition to performing statistical correlations intercorrelations. Samp...

The macrolides appear to have considerable effects for treatment of bovine mastitis because of excellent diffusion into the mammary gland, long half-life, low protein binding, high intracellular concentration and lipid solubility. Acquired resistance to macrolides in Staphylococcus aureus is primarily related to target-site modification through acquisition of an erm gene. In t...