Primary cutaneous neoplasms of myoepithelial differentiation are uncommon. Cutaneous myoepithelial carcinomas are rare. We report a case of cutaneous myoepithelial carcinoma in a 47-year-old man with a history of end-stage renal disease and renal transplant 19 years prior who presented to the hospital with a 3-month history of diffuse bone pain and an ulcerated scalp mass with multiple satellit...

Epithelial-myoepithelial carcinoma (EMC) is a rare neoplasm, which predominantly arises in the parotid gland. EMC is characterized by two types of cells; myoepithelial and epithelial cells arranged in well-defined tubules. A 48-year-old male with a six-month history of dysphagia presented with a 2-cm-diameter mass in the left posterior wall of the hypopharynx. Histopathological examination reve...

Salivary duct carcinoma (SDC) is a prototypic aggressive salivary gland carcinoma. Our aim is to determine the prevalence of histologic variants (micropapillary, basal-like) and androgen receptor (AR) expression in a large multi-institutional series of SDC. AR status was determined by immunohistochemistry (IHC). Most SDCs were characterized by an apocrine phenotype and AR expression. Cases with...

In the 4th edition of the WHO Classification of Tumours of the Breast, myoepithelial lesions are retitled myoepithelial and epithelial-myoepithelial lesions in order to better reflect the dual participation of luminal and myoepithelial compartments in some key entities. Malignant myoepithelioma, described as a section within the chapter on myoepithelial lesions in the 3rd edition, is recognised...

In addition to contraction, myoepithelia have diverse paracrine effects, including a tumor suppression effect. However, certain myoepithelial markers have been shown to contribute to tumor progression. Transforming growth factor-β (TGF-β) is involved in the transdifferentiation of fibroblasts to contractile myofibroblasts. We investigated whether TGF-β can upregulate potential myoepithelial mar...

Introduction: Myoepithelial carcinomas are rare malignant neoplasms, which known to arise from the salivary glands or other organs. Case Presentation: Here, we present a case of myoepithelial carcinoma in 64-year-old woman, presenting clinic with painful ankle mass for past three years. Ultrasonography showed 1 cm, iso- hypoechoic on medial malleolus right ankle. Magnetic resonance imaging (MRI...