PURPOSE To present a clinical case in which real-time intratreatment imaging identified an multileaf collimator (MLC) leaf to be consistently deviating from its programmed and logged position by >1 mm. METHODS An EPID-based exit-fluence dosimetry system designed to prevent gross delivery errors was used to capture cine during treatment images. The author serendipitously visually identified a ...

Introduction: Tumor control and treatment quality depend on accuracy of delivered dose. Various methods have been studied for treatment dosimetry verification. Among these methods, the use of electronic portal imaging device (EPID) is highly considered. Many efforts are underway to improve the results of this context.   Materials and Methods: In this study, ...

At the request of the COMAC EPID committee of the Commission of the European Communities the author visited all the countries of the EEC except Luxembourg in 1983-84 in order to prepare a report on 'Upgrading in epidemiology'. The report was presented at a meeting organized by COMAC EPID in April 1984 and subsequently revised and finally presented in January 1985. This paper is an abbreviated v...

Recently, with the advent of linear accelerators equipped with on-board x-ray images and advanced imaging technologies, image-guided radiotherapy (IGRT) has gained worldwide momentum in the radio therapeutic management of cancers in terms of volumetric information-based accurate tumor localization, real-time patient setup and margin reduction [1,2]. The involved technologies include digital rad...

This paper presents a bio-inspired method for in-vivo control of blood glucose based on a model of the pancreatic β-cell. The proposed model is shown to be implementable using low-power analogue integrated circuits in CMOS, realizing a biologically faithful implementation which captures all the behaviours seen in physiology. This is then shown to be capable of glucose control using an in silico...

Radiotherapy employs high energy radiation for the purpose of cancer treatment. Precise patient positioning is essential with the current use of complicated treatment plans. Portal imaging is often used for pre and during treatment anatomical setup verification. Currently the most advanced and widely used amorphous silicon Electronic portal imaging device (EPID) (aSi 1000) and the TrueBeam line...

A study was performed to determine the relative advantage of computer-controlled couch movement versus manual repositioning to correct patient setup error measured using an electronic portal imaging device (EPID). Twenty-eight on-line setup adjustment trials of anterior-posterior (AP) pelvic projections were evaluated, with 13 setups corrected by automated couch movement determined by direct fe...

The lantibiotic-synthesizing flavoprotein EpiD catalyzes the oxidative decarboxylation of peptidylcysteines to peptidyl-aminoenethiols. The sequence motif responsible for flavin coenzyme binding and enzyme activity is conserved in different proteins from all kingdoms of life. Dfp proteins of eubacteria and archaebacteria and salt tolerance proteins of yeasts and plants belong to this new family...

Background: Electronic portal imaging devices (EPIDs) play an important role in radiation therapy portal imaging, geometric and dosimetric verifications. A successful utilization of EPIDs for imaging and dosimetric purposes requires a reliable quality control process routine to be carried out regularly. In this study, two in-house phantoms were developed and analyzed for implementation in a qua...

We proposed to perform a basic dosimetry commissioning on a new imager sys-tem, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter-free (FFF) beams, then to develop an image-based quality assurance (QA) model for verification of the system delivery accuracy for intensity-modulated radiation therapy (IMRT) treat-...