Eukaryotic polypeptide elongation factor EF-1 is not only a major translational factor, but also one of the most important multifunctional (moonlighting) proteins. EF-1 consists of four different subunits collectively termed EF-1alphabeta beta'gamma and EF-1alphabeta gammadelta in plants and animals, respectively. EF-1alpha x GTP catalyzes the binding of aminoacyl-tRNA to the A-site of the ribo...

The present investigation deals with the accumulation of heavy metals in fields contaminated with fly ash from a thermal power plant and subsequent uptake in different parts of naturally grown plants. Results revealed that in the contaminated site, the mean level of all the metals (Cd, Zn, Cr, Pb, Cu, Ni, Mn and Fe) in soil and different parts (root and shoots) of plant species were found to be...

Present study consists geochemical variations and spatial distribution of trace elements (Fe, Mn, Cr, Co, Cu, Ni, Pb and Zn) of the ocean floor sediments collected along the continental shelf off East coast Tamil Nadu (Chennai to Velanganni) during the 2009 southwest monsoon period. Results indicate sand dominance with abundant calcareous debris and shell fragments. Normalisation of trace metal...

Enterotoxic factor (EF) was present and could be developed in nonagglutinable vibrios, but not the permeability factor (PF). Presence of PF without EF in Vibrio parahaemolyticus is significant. Both EF and PF were absent in V. alcaligenes.

Previously conducted studies have established that soil contamination by trace elements (TEs) around coal mines affects ecological biodiversity and human health. One of the ways to protect health surrounding population mine sites is through assessment impacts accurate procedures for establishment relevant reclamation plan. The aim study develop an applied methodological approach easily assess q...

Bovine mitochondrial elongation factor Ts (EF-Tsmt) stimulates the activity of Escherichia coli elongation factor Tu (EF-Tu). In contrast, E. coli EF-Ts is unable to stimulate mitochondrial EF-Tu. EF-Tsmt forms a tight complex with E. coli EF-Tu governed by an association constant of 8.6 x 10(10). This value is 100-fold stronger than the binding constant for the formation of the E. coli EF-Tu.T...

Altered expressions of mitochondria elongation factor Tu (EF-Tu) have been observed in certain types of cancers, including gastric cancer cell lines, but the impact of the alterations in gastric adenocarcinoma remains unclear. The purpose of this study was to investigate the expression of EF-Tu in gastric adenocarcinoma and to assess its clinical significance. A total of 104 paired resected gas...

Elongation factor Ts (EF-Ts) is the guanine nucleotide exchange factor for elongation factor Tu (EF-Tu). An important feature of the nucleotide exchange is the structural rearrangement of EF-Tu in the EF-Tu.EF-Ts complex caused by insertion of Phe-81 of EF-Ts between His-84 and His-118 of EF-Tu. In this study, the contribution of His-118 to nucleotide release was studied by pre-steady state kin...