The importance of achieving concentrations of both streptomycin and isoniazid adequate to sterilize all parent drug-susceptible organisms was empasized by in vitro studies on the prevention of emergence of mutants resistant to these drugs (1). Many factors determine the concentrations of these agents to which multiplying tubercle bacilli are exposed in the human subject: dosage; absorption and ...

Context. The Hertzsprung-Russell diagram is a key diagnostic diagram for stellar structure and evolution, which is now in use for more than 100 years. Aims. We introduce a new diagram which is based on the gravity-effective temperature diagram, but has various advantages. Methods. Our spectroscopic Hertzsprung-Russell (sHR) diagram shows the inverse of the flux-mean gravity versus the effective...

Appendix B of The Principles of Mathematics (1903) contains Russell’s first statement of his theory of logical types. This simple version of the theory is designed to block the reasoning that leads to the paradox of the Russell class. But Russell notes immediately that new problems arise. The problems culminate in the paradox of propositions. This is a problem that seems to run in exact paralle...