conclusions paracetamol 1 g stat + 3 g/24 h infusion is as effective as ketorolac 30 mg stat + 90 mg/24 h infusion in post-vats pain management, with good tolerability and a low incidence of adverse effects. results there was no significant difference between the k and p groups in pain scores in any of the evaluations. seventeen (48.6 %) and 9 (25.7 %) patients in the k and p groups, respective...

We are analyzing features of the K+ channel subunit proteins that are critical for function and regulation of these proteins. Our studies show biochemically that subunit proteins from the Shaker and Shaw subfamilies fail to assemble into a heteromultimer. The basis for this incompatibility is the sequences contained within the T1 assembly domain. For a subunit protein to heteromultimerize with ...

the effects of three  anesthetics, clove oil (co) ( 30 mgl-1), 2-phenoxy ethanol (2-pe) (0.3 mll-1), and ms-222 (100 mgl-1) were examined on blood enzymes including lactate dehydrogenase (ldh), creatine kinase (ck), alanine aminotransferase (alt), aspartate aminotransferase (ast), albumin, glucose, and cortisol levels in the caspian brown trout. blood parameters were evaluated in the control (n...

The musculo-skeletal response of athletes to various activities during training exercises has become a critical issue in order to optimize their performance and minimize injuries. However, dynamic and kinematic measures of an athlete's activity are generally limited by constraints in data collection and technology. Thus, the choice of reliable and accurate sensors is crucial for gathering data ...

The assemblage of specific ion channels and receptors at synaptic sites is crucial for signaling between pre- and postsynaptic cells. However, the mechanisms by which proteins are targeted to and clustered at synapses are poorly understood. Here we show that the product of the Drosophila discs-large gene, DLG, is colocalized with Shaker K+ channels, which are clustered at glutamatergic synapses...

BACKGROUND Current guidelines recommend withholding antithrombotic therapy (ATT) for at least 24 h in patients with acute ischemic stroke treated with thrombolytic therapy. Herein, we report a retrospective analysis of a single-centre experience on the safety and efficacy of antithrombotic therapy (ATT) started before or after 24 h of intravenous thrombolysis in a cohort of acute ischemic strok...

OBJECTIVE Anecdotal evidence shows that the Shaker exercise and its modifications improve pharyngeal muscle contraction. However, there is no experimental evidence for the same. Thus, the present study examined the effect of modified Shaker exercise on the amplitude and duration of pharyngeal muscle contraction using cervical auscultation. DESIGN The study follows a cross-sectional study desi...

background: hyperbilirubinemia is one of the most common and persistent problems encountered in preterm newborns. this condition in preterm infant is more likely to be associated with neurological damage rather than terms. so far, no major studies have precisely assessed the effects of zinc sulfate on hyperbilirubinemia in low-birth-weight (lbw) neonates. therefore, in this study, we aimed to e...