Introduction: One of most common treatments of end-stage renal disease is peritoneal dialysis. Encapsulating peritoneal sclerosis is a complication in which the osmotic capacity of the peritoneal barrier is lost, due to infections or the irritating effect of dialysis solutions. This pathology has different clinical presentations, hence the need of different diagnostic and therapeutic methods. O...

BACKGROUND Idiopathic sclerosing encapsulating peritonitis (or abdominal cocoon) is a rare cause of small bowel obstruction, especially in adult population. Diagnosis is usually incidental at laparotomy. We discuss one such rare case, outlining the fact that an intra-operative surprise diagnosis could have been facilitated by previous investigations. CASE PRESENTATION A 56 year-old man presen...

The assignment of personal probabilities to form a forensic practitioner's likelihood ratio is a mental operation subject to all the frailties of human memory, perception and judgment. While we agree that beliefs expressed as coherent probabilities are neither 'right' nor 'wrong' we argue that debate over this fact obscures both the requirement for and consideration of the 'helpfulness' of prac...

Ontology engineering on the web requires a well-defined ontology module system that allows sharing knowledge. This involves declaring modules that expose their content through an interface which hides the way concepts are modeled. We provide a straightforward syntax for such modules which is mainly based on ontology alignments. We show how to adapt a generic semantics of alignments so that it a...

We present a novel therapeutic nanoplatform based on mesoporous silica nanoparticles encapsulating ferulic acid/gemcitabine and functionalized with anti-GPC1 antibodies to target human pancreatic cancer (PANC-1) cells.