نتایج جستجو برای: emulsion solvent diffusion

تعداد نتایج: 226762  

Journal: :Small 2014
Laura R Arriaga Sujit S Datta Shin-Hyun Kim Esther Amstad Thomas E Kodger Francisco Monroy David A Weitz

A microfluidic approach is reported for the high-throughput, continuous production of giant unilamellar vesicles (GUVs) using water-in-oil-in-water double emulsion drops as templates. Importantly, these emulsion drops have ultrathin shells; this minimizes the amount of residual solvent that remains trapped within the GUV membrane, overcoming a major limitation of typical microfluidic approaches...

Journal: :the iranian journal of pharmaceutical research 0
badir delf loveymi faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. biotechnology research center, tabriz university of medical sciences, tabriz, iran. parvin zakeri-milani faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. liver and gastrointestinal diseases research center, tabriz university of medical sciences, tabriz, iran. hadi valizadeh faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran.

a box-behnken design with three replicates was used for preparation and evaluation of eudragit vancomycin (vcm) nanoparticles prepared by double emulsion. the purpose of this work was to optimize vcm nanoparticles to improve the physicochemical properties. nanoparticles were formed by using w1/o/w2 double-emulsion solvent evaporation method using eudragit rs as a retardant material. full factor...

2013
Jayesh Shivaji Patil Sunil kumar Yadav Vinod Jagganathrao mokale Jitendra Baliram Naik

The aim of this study was to prepare surfactant free Diclofenac sodium loaded ethyl cellulose nanoparticles by O/W single emulsion solvent evaporation high pressure homogenization technique.In the preparation of O/W single emulsion sodium alginate used as an emulsifying/stabilizing agent. Microparticles of nine different batches at different condition were prepared after that optimized batch wa...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2017
Fei Wu Lili Dai Lee Geng Hua Zhu Tuo Jin

Using recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) as a model drug, the present study demonstrated a practically feasible process to produce polymeric microspheres for sustained-release delivery of protein drugs with preserved integrity. This process is featured with pre-loading proteins into polysaccharide fine particles via a self-standing aqueous-aqueous "emu...

2011
Ho Cheung Shum

We present an approach to fabricate capsules consisting of a composite layer of particles and block copolymers . The capsules are fabricated by directed assembly of block copolymers at the interfaces of a double emulsion template and electrostatic adsorption of particles onto the copolymers. The double emulsion drops are prepared using capillary-based microfluidics. The solvent phase of the dou...

2016

Diclofenac sodium is a Non-Steroidal Anti-inflammatory Drug, active against relief from pain and inflammation. The main objective of this research work was to prepare Ethyl Cellulose microsphere loaded with Diclofenac and invitro drug release study. In the present study, emulsion Solvent Evaporation Method is used for preparing microsphere. The polymer (EC) and drug (Diclofenac Sodium) was diss...

Journal: :Engineering proceedings 2021

Nanoparticles were obtained by nanoprecipitation and emulsion solvent evaporation (ESE) method. In the ESE method, size of particles depended on type concentration surfactant (in water phase) polymer organic phase). The best results with ionic surfactants, however, use such compounds may accelerate degradation process polymers. ratio (methylene chloride) to non-solvent (hexane) has a significan...

Journal: :Colloids and interfaces 2023

Here, we prepared hydrophobic cryogel particles with monolithic supermacropores based on poly-trimethylolpropane trimethacrylate (pTrim) by combining the inverse Leidenfrost effect and cryo-polymerization technique. The adopting this method demonstrated separation of stabilized O/W emulsion surfactant. were characterized in terms macroscopic shape porous structure. It was found that had a narro...

1998
B. Narasimhan J. E. M. Snaar R. W. Bowtell S. Morgan C. D. Melia N. A. Peppas

Magnetic resonance imaging is used to study changing microstructure and molecular motion during dissolution of poly(vinyl alcohol) (PVA) in water. One-dimensional water concentration profiles were measured as a function of distance from the polymer-solvent interface. Diffusion-weighted profiles were used to calculate the spatial variation of the self-diffusion coefficient of water. The results ...

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