The linea alba (LA), a midline tendinous structure formed by the interlocking anterior abdominal wall aponeurotic fibers, acts as a passive tensile band that prevents sagging of the lower abdomen. The microstructure and the strength of these fibres would thus be expected to reflect on the forces that act on the linea alba. This study was undertaken to establish the histomorphology, morphometry ...

The repair of articular cartilage lesions in weight-bearing joints remains as a significant challenge due to the low regenerative capacity this tissue. Hydrogels are candidates they have similar properties extracellular matrix but unable meet mechanical and biological requirements for successful outcome. Here, we reinforce hyaluronic acid (HA) hydrogels with 13-93-lithium bioactive glass micro-...

Abstract

Elastic fibres are essential for normal physiology in numerous tissues, including arteries, lungs and skin. Fibulin-4 is an elastic-fibre-associated glycoprotein that is indispensable for elastic-fibre formation in mice. However, the mechanism by which fibulin-4 executes this function remains to be determined. Here, we established an in vitro functional assay system in which fibulin-4 was knock...

Four cases are described in which solitary nodules were identified on the anterior aspect of the liver. These had characteristic histological appearances. Each had a necrotic core surrounded by a dense collar of hyalinised collagen, incorporating elastic fibres. While three of our patients had carcinoma elsewhere none had evidence of tumour in the liver. We do not believe that these lesions rep...

Graphene fibres are continuously prepared from universal graphene oxide precursors by a novel hydrogel-assisted spinning method. With assistance of a rolling process, meters of ribbon-like GFs, or GRs with improved conductivity, tensile strength, and a long-range ordered compact layer structure are successfully obtained. Furthermore, we refined our spinning process to obtained elastic GRs with ...

BACKGROUND The purpose of this study was to investigate the effect of storage of human muscle biopsies on passive mechanical properties. METHODS Stress-strain analysis accompanied by laser diffraction assisted sarcomere length measurement was performed on single muscle fibres from fresh samples and compared with single fibres from stored samples (-20 degrees C, 4 weeks) with the same origin a...

Flight necessitates that the feather rachis is extremely tough and light. Yet, the crucial filamentous hierarchy of the rachis is unknown-study hindered by the tight chemical bonding between the filaments and matrix. We used novel microbial biodegradation to delineate the fibres of the rachidial cortex in situ. It revealed the thickest keratin filaments known to date (factor >10), approximately...