in recent years, virtual communities have been significantly popular and almost all of them are targeted for business profitability. in our study, the profitability of these communities for businesses has been analyzed from a commercial perspective. the study considers virtual community as a business model which can have a great impact on consumer purchase decision process. with respect to refe...

PURPOSE To predict Caco-2 permeability is a valuable target for pharmaceutical research. Most of the Caco-2 prediction models are based on commercial or special software which limited their practical value. This study represents the relationship between Caco-2 permeability and molecular descriptors totally based on open source software. METHODS The Caco-2 prediction model was constructed base...

12 We report on laboratory experiments designed to investigate the effect of 13 dynamic stressing on permeability of fractured rock. Berea sandstone samples 14 were fractured in-situ under triaxial stresses of 10's of MPa, and deionized 15 water was forced through the incipient fracture under conditions of steady and 16 oscillating pore pressure. We find that dynamic stresses produced by pore 1...

Nystatin and amphotericin B increase the permeability of thin (<100 A) lipid membranes to ions, water, and nonelectrolytes. Water and nonelectrolyte permeability increase linearly with membrane conductance (i.e., ion permeability). In the unmodified membrane, the osmotic permeability coefficient, P(f), is equal to the tagged water permeability coefficient, (P(d))(w); in the nystatin- or amphote...

The aim of the present study was to examine the effect of micellar systems on the absorption of beta-lapachone (b-lap) through different intestinal segments using a single-pass rat intestinal perfusion technique. B-lap was solubilized in mixed micelles composed of phosphatidylcholine and sodium deoxycholate, and in sodium lauryl sulfate (SLS)-based conventional micelles. Both mixed micelles and...

A number of mixing rules are proposed in the literature to predict the dependence of effective material parameters (permittivity and permeability) of composites on frequency and concentration. However, the existing mixing rules for frequency dependence of permeability in magnetic composites typically do not provide satisfactory agreement with measured data. Herein, a simple mixing rule is propo...

Gas reservoirs with low permeability (k<0.1 mD) are among the unconventional reservoirs and are commonly termed as "Tight Gas Reservoirs". In conventional gas reservoirs that have high permeability, the flow of gas is basically controlled by the reservoir permeability and it is calculated using the Darcy equation. In these reservoirs, gas flow due to gas diffusion is ignored compared to Dar...

The magnetic permeabiility and the thickness of the socalled %on"magnetic grain boundary were studied for a MgMnZn-femte with composition M~,J~,&ln,lFe,,,03,m For the mono-domain situation the grain size dependence of the effective initial permeability is well described by the nonmagnetic grain boundary model. A gradual increase of permeability with grain size around the transition from monoto ...

The purpose of the present article is to review recent advances made in the determination and calculation of improved bounds on the effective properties of random heterogeneous media that depend upon the microstructure via n-point correlation functions. New breakthroughs made in the quantitative characterization of the microstructure of heterogeneous materials are also reviewed. The following f...