Atopy patch testing with Japanese cedar pollen extract has been used to investigate patients with atopic dermatitis whose condition is exacerbated by contact with Japanese cedar pollen. Comparative atopy patch testing, scratch tests, and assays for total IgE and specific IgE were performed in 74 patients with atopic dermatitis, 5 patients with Japanese cedar pollinosis and 15 control subjects. ...

OBJECTIVE To evaluate the incidence, type, and severity of telaprevir-associated skin reactions. DESIGN Three dermatologists assessed available information including photographs, biopsy results, and clinical summaries of all cases with skin eruptions reported as moderate or severe during the telaprevir clinical development program. For cases from placebo-controlled trials, they were masked to...

A 39-year-old non-atopic nurse was referred to our contact allergy unit in November 2012 because of eczematous skin lesions on the arms, neck and trunk of 7-month duration. Initially, the diagnosis of pityriasis rosea of Gibert had been suspected, but a biopsy of a lesion on the trunk had shown a spongiotic dermatitis with eosinophils, compatible with eczema. Application of a cream containing h...

Food allergy may provoke flares of atopic dermatitis. The prevalence of food allergy in infants with atopic eczema (AE) may be estimated at 40%. Most of cases of food allergies concern young children (infants aged under one year), and affected by recur eczema under appropriate treatment. Cow’s milk, hen’ eggs and wheat’ flours are the main food allergens involved in food allergies associated wi...

The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Patients were divided ...

A 40-year-old woman presented with an itchy erythematosquamous change of a café-au-lait spot in her face. The onset of this change occurred just after her relocation. The café-au-lait spot had been irradiated by laser approximately 20 years ago. Clinically, there was a coin-sized erythema with a slight scale on the pigmented lesion in the left lateral orbital region. Histopathologically, the le...

BACKGROUND The influx of a large number of immigrants has altered the sociodemographic profile in Spain. To date, few studies of the skin diseases of immigrants to Spain have been done. OBJECTIVE To determine the frequency of visits by immigrants to our dermatology clinic, to describe their skin complaints, and to compare them to those of the autochthonous Spanish population. PATIENTS AND M...

Expression of serotonin (5-hydroxytryptamine; 5-HT), 5-HT receptors 1A (5-HT1AR) and 2A, and serotonin transporter protein (SERT) was studied in positive epicutaneous reactions to nickel sulphate in nickel-allergic patients, at 72 h post-challenge with the antigen. In addition, the effects of 5-HT2AR agonist 2,5-dimethoxy-4-iodoamphetamine (DOI), and the selective serotonin reuptake inhibitors ...

Paget disease of the breast is a rare cancer that accounts for 1-3% all new presentations cancer. It characterized by an eczematous and ulcerative lesion nipple may extend to areola. Nearly 90% cases are associated with underlying We report presentation in 41-year-old female, who presented due one-year history left area no palpable mass, was later found have high-grade invasive ductal carcinoma...

Atopic Dermatitis is an intermittent severely pruritic eczematous dermatitis with scaly erythematous patches, vesiculation, crusting and fissuring. It a reaction pattern that presents variable clinical histological findings. affects at least 20% of school children 5-10 %of adults. constitutes atopy, condition altered reactivity to common mild environmental stimuli. Mainly the face flexures infa...