The RAD6 gene of the yeast Saccharomyces cerevisiae encodes an enzyme that conjugates ubiquitin to other proteins. Defects in RAD6 confer a mutator phenotype due, in part, to an increased rate of transposition of the yeast T y element. To further delineate the role of protein ubiquitination in the control of spontaneous mutagenesis in yeast, we have characterized 202 mutations that arose sponta...

For an ancient solution of the mean curvature flow, we show that each time slice Mt is contained in an affine subspace with dimension bounded in terms of the density and the dimension of the evolving submanifold. Recall that an ancient solution is a family Mt that evolves under mean curvature flow for all negative time t. 0. Introduction This paper deals with ancient solutions of mean curvature...

We devised a single-step selection method to identify short sequences within the folded Rev response element (RRE) of the human immunodeficiency virus (HIV) RNA genome that are proximal and able to bind short oligonucleotides. The method employed a library of partially randomized tethered oligonucleotide probes (TOPs) complementary to all regions of the RRE and an RNase H cleavage assay which i...

S AND PRESENTATION DESCRIPTIONS SESSION 1: EDA TOOL PRESENTATIONS Catapult Synthesis: a Proven Approach for the Creation of Complex Hardware Designs Bollaert, Mentor Graphics FR How to Make Algorithmic Synthesis as Ubiquitous as Logic Synthesis V Kathail, Synfora, US Cynthesizer: the Forte SystemC synthesis tool M Meredith, Forte Design Systems, US New Opportunities for High-Level Synthesis J C...

An integrated ant colony optimization algorithm (IACS-HFS) is proposed for a multistage hybrid flow-shop scheduling problem. The objective of scheduling is the minimization of the makespan. To solve this NP-hard problem, the IACS-HFS considers the assignment and sequencing sub-problems simultaneously in the construction procedures. The performance of the algorithm is evaluated by numerical expe...

We investigated the differential regulation of two 1-aminocyclopropane-1-carboxylate synthase (ACS) genes, one 1-aminocyclopropane-1-carboxylate oxidase (ACO) gene and one ethylene response sensor (ERS1) ortholog during ripening and in response to wounding in avocados (Persea americana Mill. ‘Bacon’). The 1-aminocyclopropane-1carboxylate (ACC) content, ACS activity and detectable expression of ...

The activity of the Georgia Institute of Technology in the development of the near-field measurement technique is reviewed. The work conducted during the years 1967-1973 is given primary importance, and the major near-field developments in the 1973-1980 time period are also briefly described. HE GEORGIA Institute of Technology has historically T had a strong interest in antenna measurement tech...

Over recent decades there has been a considerable increase in the mean age at which mothers in the industrialized world give birth to their first child. For example, since 1990 in the USA, the number of pregnant women aged 45–49 years has increased 190% w2x. Similarly, there is intense debate on the increasing proportion of cesarean deliveries; however, there is little recognition of the connec...

Horticultural Sciences Department duced proteins in plants. Dominant mutations in the IAA University of Florida domain that confer insensitivity to auxin also strongly Gainesville, Florida 32611 inhibit turnover of IAA proteins (Worley et al., 2000). †The Howard Hughes Medical Institute Protein–protein interactions mediated by the IAA doThe Salk Institute for Biological Studies mains are propos...

Signaling through the redox active molecule hydrogen peroxide (H2O2) is important for several processes in plants, such as stomatal closure, root growth, gravitropism, and responses to pathogen challenge (Neill et al., 2002; Laloi et al., 2004). Although oxidative modification of reactive Cys residues within proteins hasbeen suggested as ameans bywhichH2O2 signaling can activate responses such ...