In this paper, the dynamic analysis of mental sweating for sound stimulus of a few tens of eccrine sweat glands is performed by the time-sequential piled-up en-face optical coherence tomography (OCT) images with the frame spacing of 3.3 sec. In the experiment, the amount of excess sweat can be evaluated simultaneously for a few tens of sweat glands by piling up of all the en-face OCT images. St...

Eccrine carcinoma is an extremely rare malignant skin cancer arising from eccrine sweat glands with a high metastatic potential. It mainly occurs in the elderly, with equal incidence in both sexes. It usually spreads to regional lymph nodes, with liver, lungs, and bones being the most common sites of distant metastasis. Because of tumor rarity, little is known about the value of F-18 FDG PET/CT...

The transforming growth factor-beta superfamily is thought to be involved in the regulation and control of growth and differentiation. These growth factors signal through transmembrane serine/threonine kinase receptors. The activation of type I receptor kinase phosphorylates a family of intracellular signalling proteins called Smads. In the present study, we wanted to localize type I and type I...

Angio eccrine hamartoma (EAH) is a rare, benign tumoral lesion composed of glands and vascular structures in the mid dermis. We report on two observations Dakar. Observation 1: A four-month-old infant was seen for an erythematous plaque, rounded, with smooth surface, asymptomatic, localized to right thigh, evolving three months. The clinical appearance suggested spitz tumour. Cutaneous histolog...

Antimicrobial peptides (AMPs) are effector molecules of innate immunity. Dermcidin (DCD), a recently discovered AMP with broad-spectrum activity, is produced constitutively by the eccrine sweat glands and secreted into sweat. In this study, we investigated the proteolytic processing, site-specific expression, and stability of DCD peptides in eccrine sweat. Using surface-enhanced laser desorptio...

Sweat maintains systemic homeostasis in humans. mainly includes certain metabolites, antibiotic peptides, and electrolytes. contribute to the regulation of body temperature, immune defense, moisture retention. Acquired idiopathic generalized anhidrosis (AIGA) is an intractable disease, that cause fatal heatstroke skin dryness. Although symptoms related AIGA apparently impairs patients’ QOLs, th...

Granulosis Rubra Nasi (GRN) is a rare disorder of the eccrine glands. It is clinically characterized by hyperhidrosis of the central part of the face, most commonly on the tip of the nose, followed by appearance of diffuse erythema over the nose, cheeks, chin, and upper lip. It is commonly seen in childhood but it can present in adults. Here we report a case of GRN in an adult patient with very...

The Gulf Journal of Dermatology and Venereology ABSTRACT Nodular hidradenoma is a benign neoplasm of eccrine sweat glands ductal origin. It usually presents as slowly enlarging, solitary, freely movable, solid or cystic swelling. It occurs in 2050 years age group with a female preponderance. We herein report a case of nodular hidradenoma in a 64 year old female patient who presented with an asy...

Histopathology Histological study of a 4-mm punch biopsy obtained from the center of the lesion showed a proliferation of dilated, thin-walled vessels in the superficial and deep dermis, in intimate contact with an increased density of eccrine glands of normal size and morphology, a few hair follicles, and adipose tissue. There were no visible changes in the epidermis and no mitotic figures or ...