نتایج جستجو برای: ebola virus
تعداد نتایج: 400131 فیلتر نتایج به سال:
The severe Ebola virus disease epidemic occurring in West Africa stems from a single zoonotic transmission event to a 2-year-old boy in Meliandou, Guinea. We investigated the zoonotic origins of the epidemic using wildlife surveys, interviews, and molecular analyses of bat and environmental samples. We found no evidence for a concurrent outbreak in larger wildlife. Exposure to fruit bats is com...
Ebola is a rare and deadly disease caused by infection with a strain of Ebola virus. The current 2014 Ebola epidemic outbreak in West Africa (first cases notified in March 2014) is the largest and most complex Ebola outbreak since the Ebola virus was first discovered in 1976, affecting multiple countries in West Africa. The Ebola virus causes an acute, serious illness, which is often fatal if u...
CDC is assisting ministries of health and working with other organizations to end the ongoing epidemic of Ebola virus disease (Ebola) in West Africa. The updated data in this report were compiled from situation reports from the Guinea Interministerial Committee for Response Against the Ebola Virus, the Liberia Ministry of Health and Social Welfare, the Sierra Leone Ministry of Health and Sanita...
Recent events related to the current outbreak of Ebola virus disease (EVD) in West Africa seemingly indicate inevitable problems that Europe has to face: an individual became symptomatic from Ebola virus disease only after having arrived in a non-affected country [1], and healthcare workers became infected with Ebola while caring for patients, either in West Africa or in non-affected countries ...
The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification technologies (NAT). The calibration and performance assessment of established assays and those under evaluation requires reference materials that can be used in parallel with the clinical sample to standardise or control for every step of the ...
Ebola virus budding is mediated by the VP40 matrix protein. VP40 can bud from mammalian cells independent of other viral proteins, and efficient release of VP40 virus-like particles (VLPs) requires interactions with host proteins such as tsg101 and Nedd4, an E3 ubiquitin ligase. Ubiquitin itself is thought to be exploited by Ebola virus to facilitate efficient virus egress. Disruption of VP40 f...
Clinical evidence suggests that antibodies from reconvalescent donors (persons who have recovered from infection) may be effective in the treatment of Ebola virus infection. Administration of this treatment to Ebola virus-infected patients while preventing the transmission of other pathogenic viruses may be best accomplished by use of virus-inactivated reconvalescent plasma.
We report two cases of confirmed Ebola virus disease in pregnant women, who presented at the Médecins Sans Frontières Ebola treatment centre in Guéckédou. Despite the very high risk of death, both pregnant women survived. In both cases the critical decision was made to induce vaginal delivery. We raise a number of considerations regarding the management of Ebola virus-infected pregnant women, i...
A lthough the Journal of the Advanced Prac titioner in Oncology (JADPRO) is focused on publishing issues and content specific to oncology, we recognize that the current outbreak of the Ebola virus is a critical issue and one that readers should be aware of. The Ebola virus was first noted in 1976, when two outbreaks occurred in the Sudan and the Democratic Republic of the Congo. The adjacent Eb...
Heterodimeric receptors of the beta1 and beta3 integrin families are shown to play an important role in platelet adhesion and aggregation, which is critical for homeostasis and thrombosis [11]. In particular, GPIIb/IIIa integrant complex on platelets binds to collagen, fibrinogen and Von Willebrand Factor, resulting in platelet activation. This activation triggers the coagulation cascade result...
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