نتایج جستجو برای: early onset breast cancer

تعداد نتایج: 1725716  

Journal: :Journal of medical genetics 2001
R B van der Luijt P H van Zon R P Jansen C J van der Sijs-Bos C C Wárlám-Rodenhuis M G Ausems

Germline mutations in either of the two major breast cancer predisposition genes, BRCA1 and BRCA2, account for a significant proportion of hereditary breast/ovarian cancer. Identification of breast cancer patients carrying mutations of these genes is primarily based on a positive family history of breast/ovarian cancer or early onset of the disease or both. In the course of mutation screening o...

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2012
E Kharazmi M Fallah K Sundquist K Hemminki

OBJECTIVE To determine whether familial risk of cancer is limited to early onset cases. DESIGN Nationwide prospective cohort study. SETTING Nationwide Swedish Family-Cancer Database. PARTICIPANTS All Swedes born after 1931 and their biological parents, totalling >12.2 million individuals, including >1.1 million cases of first primary cancer. MAIN OUTCOME MEASURES Familial risks of the c...

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Journal: Iranian Journal of Medical Physics 2018
Bahman Alipour Parinaz Mehnati, Roya Salehi

Introduction: Early detection and treatment of breast cancer may be helping to save the lives of patients. Many new techniques have been urban to detect breast cancer. One of them is the use of nano-particles for accuracy and early diagnosis after photo transfer. In this study, rod gold nano particles was used according their ability to change light source transfer intensity. ...

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Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
effat hatefnia dept.of health education, scool of medicine,tarbiat modarres university, tehran shamsaldin niknami dept.of health education, scool of medicine,tarbiat modarres university, tehran mahmoud mahmoudi dept. of biostatistics, school of medicine, tehran university of medical sciences, tehran fazlollah ghofranipour dept.of health education, scool of medicine,tarbiat modarres university, tehran meinour lamyian dept.of health education, scool of medicine,tarbiat modarres university, tehran

background: breast cancer is the most common cancer among women worldwide. because of unknown etiology of cancer there is no specific existing method to prevent this diseases. annual mammography is considered the most valuable tool for detecting breast cancer in the earliest possible stages. this study was conducted to determine the effects of an education program on promoting mammography behav...

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2006
Nadezhda Yu Krylova Oksana S Lobeiko Anna P Sokolenko Aglaya G Iyevleva Maxim E Rozanov Natalia V Mitiushkina Madina M Gergova Tatiana V Porhanova Adel F Urmancheyeva Sergey Ya Maximov Alexandr V Togo Evgeny N Imyanitov

The BRCA1 4153delA allele is frequently referred to as the Russian founder mutation, as it was initially detected in several cancer families from Moscow. Our earlier studies have demonstrated 1% occurrence of BRCA1 4153delA heterozygosity in familial and/or early-onset and/or bilateral Russian breast cancer (BC) patients. Since literature data suggest that the 4153delA variant is more associate...

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ژورنال: مجله پزشکی ارومیه 2010
ملکی , داود ,

Received: 3 March, 2010 Accepted: 19 May, 2010 AbstractBackground &Aims: Breast cancer after skin cancer is the most common type of cancer in women and is not preventable, but early detection through mammography improves treatment options, success, and survival. Breast cancer is the third most common malignant neoplasm in Iran (10% of all cancers). The aim of this study was to determine the age...

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ژورنال: پژوهش در پزشکی 2004
Ann Dalton, , David p. Hornby, , وحید رضا یاسایی, ,

Background: Breast cancer is the most common female malignancy and the main cause of death in  mid-aged women. Genetic germ line mutations in BRCAI/BRCA2 in Iranian women with breast or  ovarian cancer have not been yet reported. Materials and methods: Clinical data, family history and blood samples were obtained from 83  females aged less than 45 years with primary breast cancer in order to su...

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ژورنال: مجله علمی دانشگاه علوم پزشکی بیرجند 2011
اخباری, سید هادی, حسینی, مهران, شریف زاده, غلامرضا, عطایی, مرضیه, کرمانی, طیبه,

Background and Aim: Breast cancer is the most common malignancy and the first cause of cancer deaths among women in the world. The present case-control study was designed to evaluate the risk factors among the patients in South Khorasan province, Iran. Materials and Methods: In a case control study, 85 patients with breast cancer who were diagnosed during 2006 and 2008 at imam Reza hospital (bi...

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2012
MC Southey DJ Park F Lesueur F Odefrey T Nguyen-Dumont F Hammet SL Neuhausen EM John IL Andrulis G Chenevix-Trench L Baglietto F Le Calvez-Kelm M Pertesi A Lonie B Pope O Sinilnikova H Tsimiklis GG Giles JL Hopper SV Tavtigian DE Goldgar

The application of massively parallel sequencing (MPS) platforms has begun to revolutionize our understanding of the immense variation in the human genome and the complexity that can underlie genetic susceptibility to disease. The utility of exome capture MPS through the identification of genes for rare Mendelian disorders based on analysis of only a few individuals has been eloquently demonstr...

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Journal: :iranian journal of medical physics 0
alireza karimian department of biomedical engineering, faculty of engineering, university of isfahan, isfahan, iran

introduction breast cancer is one of the most common types of cancer among women.  early detection of breast cancer is the key to reducing the associated mortality rate. the presence of microcalcifications clusters (mccs) is one of the earliest signs of breast cancer. due to poor imaging contrast of mammograms and noise contamination, radiologists may overlook some diagnostic signs, specially t...

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    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->