Introduction: Perinatal mortality rate (PMR) is the most sensitive index of the health status of women and quality of maternal and child health services. Over 130 million babies are born every year, large numbers of children die soon after birth, many of them in the first 4 weeks of life (neonatal deaths) and most of them in the first week (early neonatal deaths). Objective: The objective of th...

Neonatal deaths now account for more than two-thirds of all in the first year life and about half children under-five years. Sub-Saharan Africa accounts up to 41% total burden neonatal worldwide. Our study aims describe causes mortality evaluate predictors timing death at Tamale Teaching Hospital (TTH), Ghana. This retrospective was conducted TTH located Northern All neonates who died Intensive...

BACKGROUND Strong associations between delayed initiation of breastfeeding and increased neonatal mortality (2-28 d) were recently reported in rural Ghana. Investigation into the biological plausibility of this relation and potential causal pathways is needed. OBJECTIVE The objective was to assess the effect of early infant feeding practices (delayed initiation, prelacteal feeding, establishe...

OBJECTIVE To ascertain the role of low birth weight (LBW) in neonatal mortality in a periurban setting in Bangladesh. METHODS LBW neonates were recruited prospectively and followed up at one month of age. The cohort of neonates were recruited after delivery in a hospital in Dhaka, Bangladesh, and 776 were successfully followed up either at home or, in the event of early death, in hospital. ...

Ocular dominance plasticity (ODP) following monocular deprivation (MD) is a model of activity-dependent neural plasticity that is restricted to an early critical period regulated by maturation of inhibition. Unique developmental plasticity mechanisms may improve outcomes following early brain injury. Our objective was to determine the effects of neonatal cerebral hypoxia-ischemia (HI) on ODP. T...

Pregnancies complicated by fetal haemoglobin (Hb) Bart’s disease are associated with poor perinatal outcomes, which include: early onset of hydrops fetalis, intrauterine or early neonatal death, and a higher risk of maternal pre-eclampsia.1 Even though there are case reports of survivors with or without intrauterine transfusion, postnatal regular transfusion is necessary until bone marrow trans...

Background: In mammalian ovaries, loss of over two-thirds of germ cells happens due to cell death. Nonetheless, the exact mechanism of cell death has yet to be determined. The present basic practical study was designed to detect 3 types of programmed cell death, namely apoptosis, autophagy, and necrosis, in murine embryonic gonadal ridges and neonatal ovaries.Methods: Twenty gonadal ridges and ...