نتایج جستجو برای: ear spiral

تعداد نتایج: 70373  

Journal: :The Journal of endocrinology 2009
Rusana Simonoska Annika E Stenberg Maoli Duan Konstantin Yakimchuk Anders Fridberger Lena Sahlin Jan-Ake Gustafsson Malou Hultcrantz

There are well known differences between males and females in hearing. In the present study, the role of estrogen receptor-beta (ER-beta; listed as ESR2 in the MGI Database) in hearing was investigated by comparing hearing and morphology of the inner ear in ER-beta knock-out mice (ER-beta(-/-)) with that of wild-type (WT) littermates. Hearing was analyzed with auditory brainstem response audiom...

Journal: :Development 2012
Lisa M Bank Lynne M Bianchi Fumi Ebisu Dov Lerman-Sinkoff Elizabeth C Smiley Yu-chi Shen Poornapriya Ramamurthy Deborah L Thompson Therese M Roth Christine R Beck Matthew Flynn Ryan S Teller Luming Feng G Nicholas Llewellyn Brandon Holmes Cyrrene Sharples Jaeda Coutinho-Budd Stephanie A Linn Andrew P Chervenak David F Dolan Jennifer Benson Ariane Kanicki Catherine A Martin Richard Altschuler Alisa E Koch Ethan M Jewett John A Germiller Kate F Barald

This study is the first to demonstrate that macrophage migration inhibitory factor (MIF), an immune system 'inflammatory' cytokine that is released by the developing otocyst, plays a role in regulating early innervation of the mouse and chick inner ear. We demonstrate that MIF is a major bioactive component of the previously uncharacterized otocyst-derived factor, which directs initial neurite ...

2018
Mun Young Chang Jihye Rhee Shin Hye Kim Young Ho Kim

OBJECTIVES Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761. Moreover, EGb 761 has been reported to activate Sirtuin 1 (SIRT1). The present study was designed to investigate whether EGb 761 prevents 3-NP-induced sensorineural hearing loss and determine i...

Journal: :Journal of neurotrauma 2010
Anette Fransson Jun Maruyama Josef M Miller Mats Ulfendahl

For patients with profound hearing loss, a cochlear implant is the only treatment available today. The function of a cochlear implant depends in part on the function and survival of spiral ganglion neurons. Following deafferentation, glial cell-derived neurotrophic factor (GDNF) is known to affect spiral ganglion neuron survival. The purpose of this study was to assess delayed GDNF treatment af...

Journal: :Acta otorrinolaringologica espanola 2005
J Montojo Woodeson T Heitzmann L Rubio Morales

We present a case of deficiency of the superior semicircular canal (SSCD) in a 37 years old patient that came to us because of episodes of subjective vertigo in response to intense sounds (Tullio phenomenon). The audiometry, electronistagmography, timpanometry and stapes reflexes were normal and the fistula test was negative. The CT scan showed an absence of bone overlying the superior semicirc...

Journal: :Agriculture 2023

Aiming to address the problems of low working efficiency and high damage rate roller peeling equipment in process fresh corn harvesting China, this paper theoretically analyzes mechanical motion between device ear, a high–low roll structure is proposed. This incorporates elastomeric rubber material, segmentation design, an adjustable spiral frame, selection relevant parameters given. To determi...

Journal: :Ibrain 2022

Mutations and deletions in the gene or upstream of encoding POU3F4 transcription factor cause X-linked progressive deafness DFNX2 additional neurodevelopmental disorders humans. Hearing loss can be purely sensorineural mixed, that is, with both conductive components. Affected males show anatomical abnormalities inner ear, which are jointly defined as incomplete partition type III. Current appro...

Journal: :Nihon Jibiinkoka Gakkai kaiho 1996
K Watanabe H Hakuhisa

Guinea pigs weighing 350 g each were used in this experiment. A small piece of Gelform containing 0.04 mg of E. coli derived endotoxin was set on the round window 24 hours after intraperitoneal injection of 0.02 mg endotoxin. Morphological changes in the cochlea were observed at 24 hours (previous report), 48 hours, 72 hours and 7 days after the introduction of the endotoxin into the middle ear...

2017
Pezhman Salehi Marshall X Ge Usha Gundimeda Leah Michelle Baum Homero Lael Cantu Joel Lavinsky Litao Tao Anthony Myint Charlene Cruz Juemei Wang Angeliki Maria Nikolakopoulou Carolina Abdala Matthew William Kelley Takahiro Ohyama Thomas Matthew Coate Rick A Friedman

Neuropilin-1 (Nrp1) encodes the transmembrane cellular receptor neuropilin-1, which is associated with cardiovascular and neuronal development and was within the peak SNP interval on chromosome 8 in our prior GWAS study on age-related hearing loss (ARHL) in mice. In this study, we generated and characterized an inner ear-specific Nrp1 conditional knockout (CKO) mouse line because Nrp1 constitut...

The flame forming process is widely used to manufacture ship hull plates. The saddle-shaped surfaces have different curvatures in perpendicular angles of planes and the manufacturers face an anti-clastic curvature. In this article, the manufacturing of saddle-shaped surfaces utilizing the flame forming process is investigated. The spiral irradiating scheme is used for forming. In order to study...

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