Hybrid dysgenesis is a condition found in certain interstrain hybrids of Drosophila melanogaster caused by the interaction of chromosomal and cytoplasmic factors. Germ-line abnormalities, including sterility, high mutability and male recombination, appear in the affected individuals. There are at lest two distinct systems of hybrid dysgenesis. We examined a Wisconsin wild population in two cons...

random monoallelic expression. Thus, the hypothesis of non-Mendelian inheritance remains valid, and the search for other mechanisms ensues. They do not exclude a complex situation in which both Mendelian and non-Mendelian mechanisms are at play. In the clinical part of this special issue, thyroid disorders associated with well-known genetic syndromes are carefully analyzed and reviewed. First, ...

ohtahara syndrome or ealy infantile epileptic encephalopathy is a rare cause of epileptic seizures during infancy and represents the earliest type of age related symptomatic generalized epilepsies. the main etiologic factor associated with ohtahara syndrome is cerebran dysgenesis. this case was the product of in vitro fertilization (ivf) after 18 years of infertility . neuroimaging findings con...