The use of magnetic resonance imaging (MRI) for the assessment of breast lesions was first described in the 1970s; however, its wide application in clinical routine is relatively recent. The basic principles for diagnosis of a breast lesion rely on the evaluation of signal intensity in T2-weighted sequences, on morphologic assessment and on the evaluation of contrast enhancement behaviour. The ...

In this study, we propose a novel scheme for real time dynamic magnetic resonance imaging (dMRI) reconstruction. Different from previous methods, the reconstructions of the second frame to the last frame are independent in our scheme, which only require the first frame as the reference. Therefore, this scheme can be naturally implemented in parallel. After the first frame is reconstructed, all ...

The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue (1)H(2)O relaxation and thus MR image intensity. For longitudinal relaxation [R(1) identical with (T(1))(-1)], the CR must have transient molecular interactions with water. Because the CR and water molecules are never uniformly distributed in the histological-scale tissue comp...

PURPOSE To clinically evaluate a highly accelerated T1-weighted dynamic contrast-enhanced (DCE) MRI technique that provides high spatial resolution and whole-brain coverage via undersampling and constrained reconstruction with multiple sparsity constraints. METHODS Conventional (rate-2 SENSE) and experimental DCE-MRI (rate-30) scans were performed 20 minutes apart in 15 brain tumor patients. ...

Background: In breast magnetic resonance imaging (MRI) analysis for lesion detection and classification, radiologists agree that both morphological and dynamic features are important to differentiate benign from malignant lesions. We propose a multiple classifier system (MCS) to classify breast lesions on dynamic contrast-enhanced MRI (DCE-MRI) combining morphological features and dynamic infor...

Introduction: The motion and the anatomy of the temporomandibular joint (TMJ) is very complex. Static or pseudo-dynamic MRI of the TMJ does not allow for full analysis of the disc deformation and displacement during the mandibular motion. The purpose of this study was to develop and evaluate a fast dynamic MRI technique for measurement of the TMJ with an arbitrary reconstruction window time poi...

Background: The diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) map and the dynamic contrast-enhanced magnetic resonance (DCE-MRI) constitute functional MRI technique many oncological applications as it can define tissue microstructure characterize post-treatment changes from a recurrent tumor in treated head neck squamous cell carcinoma (HNSCC). Objective: To evaluat...

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is being used in oncology as a noninvasive method for measuring properties of the tumor microvasculature. There is potential for DCE-MRI to be used as an imaging biomarker to measure antiangiogenic effects of cancer treatments. This article reviews the general methodology for performing DCE-MRI and discusses existing data and challe...