Rietveld analysis of X-ray powder diffraction patterns recorded from 28 hydroxyapatite (HAp) samples containing various amounts of zinc (0, 1.6, 3.2 and 6.1wt.% Zn) and heat treated at various temperatures (between 500°C and 1100°C) has enabled the Zn insertion mechanism into the HAp crystal structure to be finely characterized. The formation of Zn-doped HAp was achieved above 900°C only. Zn-do...

Accurate characterization of pure silicon-substituted hydroxyapatite powders 1 synthesized by a new precipitation route 2 David MARCHAT, Maria ZYMELKA, Cristina COELHO, Laurent GREMILLARD, 3 Lucile JOLY-POTTUZ, Florence BABONNEAU, Claude ESNOUF, Jérôme 4 CHEVALIER, Didier BERNACHE-ASSOLLANT 5 1 Ecole Nationale Supérieure des Mines, CIS-EMSE, CNRS:FRE3312, F-42023 158 cours 6 Fauriel Saint-Etien...

In a previous paper (1) it was shown that discrimination against strontium as compared to calcium, in the formation of synthetic hydroxyapatite, Calo(POJ)6(OH)2, was greater in large, more slowly grown crystals than in small, more rapidly precipitated crystals. The exclusion of strontium as compared to calcium in the hydroxyapatite crystals increases as the preparation conditions approach equil...

Hydroxyapatite is the mineral component of human bones and teeth enamel and is used as synthetic biomaterial. It also grows outside bioglasses as a response of their incorporation in body fluids. The focus is then on understanding the microscopic steps occurring at its surfaces as this allows researchers to understand the key features of biomolecular adhesion. This perspective article deals wit...

A layer-by layer technique was successfully used to obtain collagen/hydroxyapatite-magnetite-cisplatin (COLL/HAn-Fe3O4-CisPt, n=1-7) composite materials with a variable content of hydroxyapatite intended for use in the treatment of bone cancer. The main advantages of this system are the possibility of controlling the rate of delivery of cytostatic agents, the presence of collagen and hydroxyapa...

Mechanical properties of bones are largely determined by their microstructure. The latter comprises a large number of diverse pores. The present paper analyzes a connection between structure of the porous space of the osteonal cortical bone and bone's overall anisotropic elastic moduli. The analysis is based on recent developments in the theory of porous materials that predict the anisotropic e...

The concentration of structural hydroxyl groups in the apatite mineral of enamel, dentin and cementum of healthy human teeth was estimated by reference to stoichiometric hydroxyapatite to be 73 +/- 3, 18 +/- 2 and 18 +/- 1%, respectively.

Hepatocyte cell aggregation and adhesion to HAp nanocrystals covered with SU-8 polymer micropatterns by nano/microfabrication techniques is demonstrated. The surface roughness and wettability of the HAp nanocrystals are significantly different from those of the SU-8 polymer. QCM-D and microscopic observation clearly reveal that the cells realize the surface properties to form aggregation and pr...

A novel approach for depositing hydroxyapatite (HA) films on titanium substrates by using mechanical alloying (MA) technique has been developed. However, it was shown that one-hour heat treatment at 800°C of such mechanically coated HA layer leads to partial transformation of desired HA phase to beta-tri-calcium phosphate (β-TCP) phase. It appears that the grain boundary and interface defects f...

Biomaterials with antibacterial activity are widely developed for the treatment of bone infection. In the present study, hydroxyapatite (HAp) nanorods were prepared by green synthesis using Azadirachta indica and Coccinia grandis leaf extract. The prepared samples were characterized by various characterization techniques and the results indicate that the prepared samples are constituted of phas...