Radioisotopes decay by emission of radiation and energy they posses, can be utilized in wide range of agricultural applications. Nuclear scientists and technologist are unlocking the secrets of many agricultural problems, which could not have been possible with conventional methods. Radioisotopes were used for producing high yielding crop seeds to increase the agricultural yield. Radioisotopes ...

Over the last 20 years, the impact of imaging on the clinical sciences has been immense. Tremendous progress has been made in medical imaging of the human body since the invention of computed tomography (CT) and magnetic resonance imaging (MRI). Neuroimaging of patients with metal neurotoxicity can be divided into two types: morphological neuroimaging (anatomy-based imaging) including CT and MR...

Here we introduce diffusion molecular retention (DMR) tumor targeting, a technique that employs PEG-fluorochrome shielded probes that, after a peritumoral (PT) injection, undergo slow vascular uptake and extensive interstitial diffusion, with tumor retention only through integrin molecular recognition. To demonstrate DMR, RGD (integrin binding) and RAD (control) probes were synthesized bearing ...

OBJECTIVE To compare the diagnostic performance of a new dedicated ultrafast solid-state cardiac camera (Discovery NM 530c [DNM]) with standard dual detector cameras (S-SPECT) in myocardial perfusion imaging. The primary goal was a per-patient analysis of diagnostic performance of the DNM using S-SPECT as the reference standard. METHODS AND RESULTS In total, 168 patients underwent one-day Tc-...

Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion). Tomographic imaging was performed 24 hr after the intravenous inje...

BACKGROUND Myocardial viability in area at risk of acute myocardial infarction (AMI) after reperfusion therapy may be underestimated by the 24-hour images due to reverse redistribution (r-RD). METHODS Subjects were 37 AMI patients in whom Tc-99m pyrophosphate (PYP)/Tl-201 dual-isotope SPECT was positive. The 24-hour delayed scan was performed with only a Tl window. One month later, follow up ...

A rotation-based Monte Carlo (MC) simulation method (RMC) has been developed, designed for rapid calculation of downscatter through non-uniform media in SPECT. A possible application is downscatter correction in dual isotope SPECT. With RMC, only a fraction of all projections of a SPECT study have to be MC simulated in a standard manner. The other projections can be estimated rapidly using the ...

OBJECTIVE AND METHODS The aim of this study was to evaluate myocardial viability in patients after acute myocardial infarction (AMI). We compared 201Tl SPECT after 201Tl with GIK (10% glucose 250 ml, insulin 5 U and KCl 10 mEq) infusion (GIK-201Tl) with resting 201Tl and 99mTc-pyrophosphate (PYP) dual SPECT, positron emission computed tomography (PET) using 18F-fluorodeoxyglucose (18F-FDG) in 2...

In single photon emission computed tomography (SPECT), accurate attenuation maps are needed to perform essential attenuation compensation for high quality radioactivity estimation. Formulating the SPECT activity and attenuation reconstruction tasks as coupled signal estimation and system parameter identification problems, where the activity distribution and the attenuation parameter are treated...