In recent years, endothelial keratoplasty has been commonly used as an alternative to penetrating keratoplasty as a surgical treatment for corneal endothelial pathologies. The most common form of endothelial keratoplasty is Descemet membrane stripping automated endothelial keratoplasty (DSAEK), which involves stripping the host’s Descemet membrane and endothelium and replacing them with donor p...

BACKGROUND Descemet's stripping automated endothelial keratoplasty (DSAEK) surgery offers a more standardized approach and reliable method to create corneal grafts with an instrument such as a microkeratome. With the development of Descemet's membrane endothelial keratoplasty, an excellent clinical outcome is seen in the treatment of corneal endothelial dysfunctions, which indicates that thinne...

PURPOSE To report changing trends in indications and techniques of corneal transplantation in Iran. METHODS We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers throughout Iran. RESULTS The most common indication for corneal transplantation was keratoconus (KCN, n = 21,350 eyes, 45.3%), followed by bullous k...

PURPOSE We used a rabbit model to evaluate the interface embedded between the recipient corneas and transplanted donor corneal discs after non-Descemet's stripping automated endothelial keratoplasty (nDSAEK). METHODS Unilateral DSAEK and nDSAEK surgeries were performed on New Zealand white rabbits. In vivo confocal microscopy was performed to show: the changes in corneal endothelial cells emb...

PURPOSE Descemet stripping automated endothelial keratoplasty (DSAEK) can be performed with donor tissue prepared with a microkeratome either by the surgeon at the time of surgery or by a technician in the eye bank days before surgery. Are the complications and endothelial survival affected by donor preparation by a surgeon vs a technician? METHODS A single surgeon at a referral practice perf...

PURPOSE To compare clinical and confocal scan outcomes after Descemet stripping automated endothelial keratoplasty (DSAEK) performed for Fuchs' endothelial dystrophy (FED) versus pseudophakic bullous keratopathy (PBK). METHODS This retrospective comparative study included 47 consecutive eyes of 39 patients with the diagnosis of FED (n = 29, group 1) or PBK (n = 18, group 2) that underwent DSA...

PURPOSE We demonstrated a novel automated algorithm for segmentation of intraoperative optical coherence tomography (iOCT) imaging of fluid interface gap in Descemet stripping automated endothelial keratoplasty (DSAEK) and evaluated the effect of intraoperative maneuvers to promote graft apposition on interface dimensions. METHODS A total of 30 eyes of 29 patients from the anterior segment ar...