Losses at every stage in the food system influence the extent to which nutritional requirements of a growing global population can be sustainably met. Inefficiencies and losses in agricultural production and consumer behaviour all play a role. This paper aims to understand better the magnitude of different losses and to provide insights into how these influence overall food system efficiency. W...

Sigma receptors (σRs) are structurally unique proteins that function intracellularly as chaperones. Historically, σRs have been implicated as modulators of psychomotor stimulant effects and have at times been proposed as potential avenues for modifying stimulant abuse. However, the influence of ligands for σRs on the effects of stimulants, such as cocaine or methamphetamine, in various preclini...

A large body of evidence supports the hypothesis that mesolimbic dopamine (DA) mediates, in animal models, the reinforcing effects of central nervous system stimulants such as cocaine and amphetamine. The role DA plays in mediating amphetamine-type subjective effects of stimulants in humans remains to be established. Both amphetamine and cocaine increase norepinephrine (NE) via stimulation of r...

BACKGROUND To validate the association between country-of-birth and disparities in the stimulant use for ADHD among individuals in Western Australia. METHODS Using linked data, a population-based retrospective cohort of individuals admitted to hospital before age 25 years was followed through to identify having stimulants for ADHD in 2003-2007. Multivariate logistic and linear regressions wer...

Free radicals and oxidative stress are involved in the pathogenic mechanisms of cardiovascular disease (CVD), diabetes and cancer. Exercise is a useful strategy for preventing CVD but in elderly persons it can enhance oxidative stress, which is why some studies recommend antioxidant supplementation for exercising elderly subjects. This intervention study was performed on 320 elderly subjects fo...

Recently, interest in plant-derived food additives has grown mainly because synthetic antioxidants suffer from several drawbacks. Some plants are traditionally used for both food and medicine in Iran. Aqueous and methanolic extracts of Smyrnium cordifolium Boiss leaves and stems and Sinapis arvensis L leaves, stems and flowers were prepared and evaluated for their total phenolic content (TPC), ...

D oes your paediatrician have difficulty concentrating during lectures, particularly those on molecular biology and healthcare planning? When taking a history, does your paediatrician not listen properly and keep asking the same questions? Is your paediatrician too busy to spend any time with his or her own children? These are all signs of ADHD(P), a newly described phenotype of attention defic...

Disruption of the skin barrier function caused by epidermal hyper-proliferation, results in the skin becoming dry and showing high transepidermal water loss (TEWL). Gamma linolenic acid (GLA) is reportedly efficacious for treating TEWL and epidermal hyper-proliferation. In this study, to elucidate the effect of GLA-rich oil on skin function, GLA-containing food was given to adults with dry skin...