OBJECTIVES Consistent evidence has shown that young people are significantly overrepresented among victims of violence due to another person's drinking. Yet little research has examined factors that explain alcohol-related victimization among young adults, particularly in Canada. The present study examines the influence of hazardous drinking and illicit drug use on the likelihood of experiencin...

BACKGROUND For the past two decades, there has been an enduring HIV epidemic among injecting drug users (IDUs) in India, and the Indian national AIDS control program (NACP) led by the National AIDS Control Organization (NACO) has kept IDUs at the forefront along with other key populations, in its efforts to prevent HIV. Given this, the objective of this study is to examine the association betwe...

OBJECTIVES A major measure of treatment success for drug users undergoing rehabilitation is the ability to enter the workforce and generate income. This study examines the absenteeism and productivity among people who inject drugs (PWID) enrolled in methadone maintenance treatment (MMT) in Northern Vietnam. SETTING We conducted a cross-sectional study in two clinics in Tuyen Quang province. ...

Civil aviation pilots represent a small subsection of the general population. Therefore, one might expect to see the same types of drugs used by pilots that are found in the general population. The purpose of this study was to compare usage of both illegal drugs and abused prescription medications in pilots involved in civil aviation accidents from 1990 to 2005 with that of the general populati...

A field survey method was used to examine the relationship between psychopathology and acute adverse reactions to psychoactive drugs. A paper-andpencil measure of acute adverse reactions was discussed. Acute adverse reactions were hypothesized to covary positively with regression, schizophrenia, and drug usage, and to covary negatively with adjustment and paranoia. These hypotheses were support...

Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual-level phenotypes despite the promise of biomarker-driven repositioning. In this study, we propose a framework for discovering serendipitous interactions between drugs and routine clinical phenotypes in cross-secti...

OBJECTIVE To assess factors associated with drug-related harms related to policing among injection drug users (IDUs) in Tijuana, Mexico. METHODS IDUs who were over 18 years old and had injected drugs within the last six months were recruited via respondent-driven sampling and underwent questionnaires and testing for HIV (human immunodeficiency virus), syphilis and TB (tuberculosis). Random ef...

I t has been pointed out that HIV positive patients with a history of drug misuse are less likely to undergo antiretroviral therapy (ART) than those who belong to other categories of transmission. 2 Moreover, inadequate use of ART in injecting drug users (IDUs) is controversial because of the risk of parenteral and/or sexual transmission of drug resistant HIV variants. The aim of this study was...

The majority of natural history studies of human immunodeficiency virus (HIV) infection have immune and viral parameters in men. Data demonstrating that women have lower HIV-1 RNA levels than men at the same CD4 cell counts have raised the question of immunologic differences in HIV-seropositive women. This study describes levels and changes in phenotypic markers of immune maturity, function, an...

BACKGROUND To examine the predictors of continued drug- and sex-related HIV-risk behaviors among drug users in methadone maintenance therapy (MMT) programs in China. METHODS We followed a sample of 5,035 drug users enrolled for the first time in MMT programs at baseline, 6 months, and 12 months utilizing a longitudinal prospective study design. Drug users' HIV-risk behaviors, MMT characterist...