non-medical use of prescription drugs (also known as medication diversion) is a common problem in middle and low income countries where monitoring capacities and law enforcement mechanisms are not efficiently developed (1-3). prescribed central nervous system (cns) stimulants, sedative hypnotics and long-lasting opioids are the most important drugs diverted throughout the world (1-4). non-medic...

Background Determining burden of pulmonary tuberculosis (PTb) may be associated with success of directly observed theraphy (DOT) services in high PTb areas, such as Gambella, Ethiopia. Objective To assess burden of sputum smear positive SSP-PTb reports in Gambella Regional Hospital, in two consecutive years: mid 2013 to 2015. Methods From March 2013 to February 2015, PTb suspected patients'...

MULTIPLE SCLEROSIS MSJ JOURNAL Rebuttal Multiple sclerosis (MS) is a complex and heterogeneous disease in which different pathological substrates, including inflammation, demyelination, remyelination, gliosis, and axonal loss, all contribute, simultaneously or consecutively, to its clinical manifestations and accumulation of irreversible disability. At present, magnetic resonance imaging (MRI) ...

personalized medicine aims is to supply the proper drug to the proper patient within the right dose. pharmacogenomics (pgx) is to recognize genetic variants that may influence drug efficacy and toxicity. all things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient gene...

prescriptions written by general practitioners and medical specialists were studied and compared to determine the type, time of onset and clinical importance of drug-drug interactions (ddis) in an attempt to reduce further complications. in 2007, 28, 956, 638 prescriptions and 15, 610, 912 prescriptions in 2008 were filled by pharmacies affiliated with medical science universities. these prescr...

results: a total number of 117 patients were evaluated for adverse drug reactions, among them, 97 (82.9%) were considered to have immunological drug reactions. the most common symptoms of allergic drug reactions were morbilliform eruptions, serum sickness, dress (drug rash with eosinophilia and systemic symptoms), and toxic epidermal necrolysis. in 62 patients, anticonvulsant drugs had the prom...

conclusions as the results showed, the trend of activities was encouraging and some additional activities could be included to future programs relying on early-onset preventions. results summarizing the data led to three distinguished sections: 1) drug supply reduction activities; 2) drug demand reduction activities; 3) harm reduction activities. evidence acquisition in this report, authors gat...